Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 136127..136752 Replicon chromosome
Accession NZ_CP017482
Organism Pectobacterium polaris strain NIBIO1392

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag BJK05_RS00590 Protein ID WP_005976087.1
Coordinates 136127..136330 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag BJK05_RS00595 Protein ID WP_005976089.1
Coordinates 136384..136752 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJK05_RS00560 131594..131932 + 339 WP_039485501.1 P-II family nitrogen regulator -
BJK05_RS00565 131972..133258 + 1287 WP_167385195.1 ammonium transporter AmtB -
BJK05_RS00570 133386..134249 - 864 WP_095698773.1 acyl-CoA thioesterase II -
BJK05_RS00575 134462..135043 + 582 WP_095698774.1 YbaY family lipoprotein -
BJK05_RS00580 135063..135383 - 321 WP_010282239.1 MGMT family protein -
BJK05_RS00590 136127..136330 - 204 WP_005976087.1 hemolysin expression modulator Hha Toxin
BJK05_RS00595 136384..136752 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
BJK05_RS00600 137350..137493 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
BJK05_RS00605 137511..137759 - 249 WP_015839361.1 type B 50S ribosomal protein L31 -
BJK05_RS00610 137992..141120 - 3129 WP_095698775.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T66891 WP_005976087.1 NZ_CP017482:c136330-136127 [Pectobacterium polaris]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T66891 NZ_CP017482:c136330-136127 [Pectobacterium polaris]
ATGAAAAAAATCGACTATTTGATGCGTTTGCGTAAATGCACAACCATTGACACTCTCGAACGCGTTATTGAAAAAAACAA
GTATGAACTCTCCAATGATGAACTGGAGATGTTCTTTTCCGCAGCGGATCATCGTCTGGCAGAGCTGACGATGAACAAAC
TCTACGACAAAGTCCCTACTGCAGTATGGCGATACGTTCGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT66891 WP_005976089.1 NZ_CP017482:c136752-136384 [Pectobacterium polaris]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp

>AT66891 NZ_CP017482:c136752-136384 [Pectobacterium polaris]
ATGGATGAGTACACACCAAAACATTATGATATTGCCCAACTCAGATTCTTATGTGAGAATCTGTGTGACGAAAGCATAGC
AACGTTAGGTGATAGCAGTCACGGCTGGGTCAATGATCCAACATCTGCGATCAATCTCCAATTAAATGAACTTATTGAGC
ATATCGCTACGTTTATTCTCACATTTAAAATAAAATACCCTAACGAAAGTGAGCTTTCAGAGCAGGTTGAAAAGTATTTG
GATGATACTTACGTCTTGTTTAGCAACTATGGAATTAATGATGCTGAACTGCGGCGTTGGCAGAAGTCCAAAGCAAAATT
ATTCGGAATGTTCTCAGGGGAGAACGTCTGTACGCCTGCTAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References