Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2901661..2902214 Replicon chromosome
Accession NZ_CP017481
Organism Pectobacterium polaris strain NIBIO1006

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag BJJ97_RS12995 Protein ID WP_095994208.1
Coordinates 2901900..2902214 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag BJJ97_RS12990 Protein ID WP_095994207.1
Coordinates 2901661..2901897 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ97_RS12975 2898340..2898552 + 213 Protein_2502 XRE family transcriptional regulator -
BJJ97_RS12980 2898725..2900020 + 1296 WP_095994206.1 hypothetical protein -
BJJ97_RS12985 2900655..2901596 + 942 Protein_2504 DUF1738 domain-containing protein -
BJJ97_RS12990 2901661..2901897 + 237 WP_095994207.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
BJJ97_RS12995 2901900..2902214 + 315 WP_095994208.1 CcdB family protein Toxin
BJJ97_RS22195 2902248..2902514 - 267 WP_193438336.1 Arm DNA-binding domain-containing protein -
BJJ97_RS13010 2902875..2903672 - 798 WP_095994209.1 DgsA anti-repressor MtfA -
BJJ97_RS13020 2903913..2904299 - 387 WP_095994210.1 lysozyme inhibitor LprI family protein -
BJJ97_RS13025 2904453..2904620 + 168 WP_010280855.1 YqaE/Pmp3 family membrane protein -
BJJ97_RS13030 2904702..2906177 - 1476 WP_095994211.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2886136..2902514 16378


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11549.50 Da        Isoelectric Point: 7.9859

>T66888 WP_095994208.1 NZ_CP017481:2901900-2902214 [Pectobacterium polaris]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPLQALG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

>T66888 NZ_CP017481:2901900-2902214 [Pectobacterium polaris]
ATGCAATTCACAGTATACGGTAATACCGGGAAAAGCGTCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAATTGAATCGTCGGATAGTGATCCCATTGCTCCCTATTGAAAAGTATCCGGCAGGCCGCCGACCGGATCGCCTTGTCC
CCGTCGTCAGGCTGACGGACGGCAAAGAATACGCCGTAATGACCCACGAGCTGGCAAGTATTCCTCTCCAGGCTCTGGGT
GCAGTGTTTTGTGATGCGTCGCAGTACCGTACTCAGGTAAAGGCGGCAATAGACTTCCTCATCGACGGGTTCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9073.20 Da        Isoelectric Point: 6.4631

>AT66888 WP_095994207.1 NZ_CP017481:2901661-2901897 [Pectobacterium polaris]
MTAKQRNTQSVTMTVERALLVRAREAGMNLSAILSTALDAELRRHEAKKWQEENREAIDALNRFHDENGCFSDEYRMF

Download         Length: 237 bp

>AT66888 NZ_CP017481:2901661-2901897 [Pectobacterium polaris]
ATGACCGCGAAACAGCGCAACACGCAGAGCGTGACCATGACAGTAGAGCGTGCCTTACTAGTAAGAGCGCGTGAAGCGGG
TATGAACCTGAGTGCTATTCTGTCAACCGCACTGGATGCGGAGCTTCGCCGTCATGAAGCGAAAAAATGGCAGGAAGAAA
ACAGGGAGGCTATCGACGCATTAAATCGTTTTCATGATGAAAACGGCTGTTTCAGTGATGAATACAGGATGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References