Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1932303..1932963 Replicon chromosome
Accession NZ_CP017481
Organism Pectobacterium polaris strain NIBIO1006

Toxin (Protein)


Gene name cptA Uniprot ID A0A093S6F1
Locus tag BJJ97_RS08810 Protein ID WP_039487287.1
Coordinates 1932550..1932963 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A093SCR9
Locus tag BJJ97_RS08805 Protein ID WP_039487284.1
Coordinates 1932303..1932569 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ97_RS08785 1928296..1929300 - 1005 WP_095993679.1 substrate-binding domain-containing protein -
BJJ97_RS08790 1929355..1929963 - 609 WP_095701613.1 HD domain-containing protein -
BJJ97_RS08795 1930364..1931011 + 648 WP_039487281.1 hemolysin III family protein -
BJJ97_RS08800 1931066..1932067 - 1002 WP_095993680.1 tRNA-modifying protein YgfZ -
BJJ97_RS08805 1932303..1932569 + 267 WP_039487284.1 FAD assembly factor SdhE Antitoxin
BJJ97_RS08810 1932550..1932963 + 414 WP_039487287.1 protein YgfX Toxin
BJJ97_RS08815 1933032..1933967 + 936 WP_095993681.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
BJJ97_RS08820 1934033..1934356 - 324 WP_095993682.1 hypothetical protein -
BJJ97_RS08825 1934385..1934903 - 519 WP_095993683.1 flavodoxin FldB -
BJJ97_RS08830 1935243..1935629 - 387 WP_095993684.1 thioesterase family protein -
BJJ97_RS08835 1935853..1937175 - 1323 WP_039487297.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16297.28 Da        Isoelectric Point: 10.6913

>T66885 WP_039487287.1 NZ_CP017481:1932550-1932963 [Pectobacterium polaris]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQKNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLRAVNGKDKQQLWLASDSMGDEEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

>T66885 NZ_CP017481:1932550-1932963 [Pectobacterium polaris]
GTGGCCCAGTGGCAATGTGACCTTCGTGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCATGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAAGAATATCAAATCCCGACAGGGGGAAATCGTTCTGCTTAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTGCTGTCATTGCGAGCGGTTAACGGTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGTGATGAAGAGTGGCGTCACTTGCGTCAGCTTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10489.90 Da        Isoelectric Point: 5.1392

>AT66885 WP_039487284.1 NZ_CP017481:1932303-1932569 [Pectobacterium polaris]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRIISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT66885 NZ_CP017481:1932303-1932569 [Pectobacterium polaris]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGTCGCCGTGGTATGCGCGAACTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACGGATAAGCGCACGTTTGTCCGCTTGTTACAAAGCGACGATCCTGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATTATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A093S6F1

Antitoxin

Source ID Structure
AlphaFold DB A0A093SCR9

References