Detailed information of TA system TA066883

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1680352..1680935
• Replicon: chromosome
• Accession: NZ_CP017481
• Organism: Pectobacterium polaris strain NIBIO1006

Toxin (Protein)

• Gene name: parE
• Uniprot ID: A0A7V8QAI8
• Locus tag: BJJ97_RS07620
• Protein ID: WP_012822278.1
• Coordinates: 1680630..1680935 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BJJ97_RS07615
• Protein ID: WP_095993544.1
• Coordinates: 1680352..1680642 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJJ97_RS07595	1675487..1676748	-	1262	Protein_1458	L-rhamnose isomerase	-
BJJ97_RS07600	1676745..1678235	-	1491	WP_095993542.1	rhamnulokinase	-
BJJ97_RS07605	1678572..1679411	+	840	WP_095993543.1	HTH-type transcriptional activator RhaS	-
BJJ97_RS07610	1679436..1680290	+	855	WP_095701452.1	helix-turn-helix domain-containing protein	-
BJJ97_RS07615	1680352..1680642	+	291	WP_095993544.1	ribbon-helix-helix protein, CopG family	Antitoxin
BJJ97_RS07620	1680630..1680935	+	306	WP_012822278.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJJ97_RS07625	1680995..1682704	-	1710	WP_095993545.1	ABC transporter ATP-binding protein	-
BJJ97_RS07630	1682701..1683567	-	867	WP_039482013.1	ABC transporter permease	-
BJJ97_RS07635	1683560..1684519	-	960	WP_095993546.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11634.48 Da
• Isoelectric Point: 9.4590

>T66883 WP_012822278.1 NZ_CP017481:1680630-1680935 [Pectobacterium polaris]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Nucleotide

• Length: 306 bp

>T66883 NZ_CP017481:1680630-1680935 [Pectobacterium polaris]
ATGCCACAAGTGATTGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCAGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGCCATGATGAA
CTGACAGACAGAGTGGTGATACTAACCGTCAAGCATCAAAAAGAAGCGGGTTACCAAAACCCTTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11054.14 Da
• Isoelectric Point: 4.6402

>AT66883 WP_095993544.1 NZ_CP017481:1680352-1680642 [Pectobacterium polaris]
MADTPRQTTTLRIDQDIKERLKTLADDLHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT66883 NZ_CP017481:1680352-1680642 [Pectobacterium polaris]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCTCCATAGCTCAGCCCATGCGCTGATGCTGGAAGCCATTGCCGAATACGTGGAGCGCGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAACACTGGCGAACACATCACCGCAGATGAGACTGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA

Structures

Toxin

• AlphaFold DB: A0A7V8QAI8