Detailed information of TA system TA066881

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 1552051..1552582
• Replicon: chromosome
• Accession: NZ_CP017481
• Organism: Pectobacterium polaris strain NIBIO1006

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: A0A249QBN7
• Locus tag: BJJ97_RS07040
• Protein ID: WP_039493031.1
• Coordinates: 1552295..1552582 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: BJJ97_RS07035
• Protein ID: WP_095993472.1
• Coordinates: 1552051..1552305 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJJ97_RS07010	1547401..1547991	-	591	WP_011091952.1	DnaA initiator-associating protein DiaA	-
BJJ97_RS07015	1548055..1548450	-	396	WP_072009247.1	YraN family protein	-
BJJ97_RS07020	1548408..1550426	-	2019	WP_095993470.1	penicillin-binding protein activator	-
BJJ97_RS07025	1550488..1551375	+	888	WP_095993471.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
BJJ97_RS07035	1552051..1552305	+	255	WP_095993472.1	plasmid stabilization protein	Antitoxin
BJJ97_RS07040	1552295..1552582	+	288	WP_039493031.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJJ97_RS07045	1552759..1553544	+	786	WP_095993473.1	4,5-DOPA dioxygenase extradiol	-
BJJ97_RS07050	1553730..1554890	-	1161	WP_095701320.1	glutathionylspermidine synthase family protein	-
BJJ97_RS07055	1554902..1555576	-	675	WP_095701321.1	DUF1190 family protein	-
BJJ97_RS07060	1555848..1557242	-	1395	WP_095993474.1	outer membrane channel protein TolC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10993.93 Da
• Isoelectric Point: 10.7694

>T66881 WP_039493031.1 NZ_CP017481:1552295-1552582 [Pectobacterium polaris]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Nucleotide

• Length: 288 bp

>T66881 NZ_CP017481:1552295-1552582 [Pectobacterium polaris]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCGCTGAAGGAATGGAAAAAGTTAGGGCATCCTGTCCGGGAGCAATTCAA
GAAAAAACTGGTTGAGCGCTTGGAAAATCCTCGTGTTCCTTCAGCACAGCTTCATGGCCGTAAAGACCAGTATAAAATTA
AACTGAAGTCCGCTGGCTACAGGCTGGTGTATTTGGTCCAGGATGAGACCATTACTGTGATGGTTATGGGGGTGGGAAAG
CGCGAAGGTAGCCAGATTTATTCTGATACTAAAGGTCGCTCTGCTTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9236.44 Da
• Isoelectric Point: 3.7947

>AT66881 WP_095993472.1 NZ_CP017481:1552051-1552305 [Pectobacterium polaris]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPVFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT66881 NZ_CP017481:1552051-1552305 [Pectobacterium polaris]
ATGGCTTTCAACATCCTAACTAACACTGCGGCCAGTATTACTGAGTTGAAACGTGACCCTATGGGGACGGTACGGGCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGGAATGAACCGGTGTTCTACTGTGTGCCTCCTGCCGTATTCGCATATTTAA
TGGAACTGGCCGAAGATGCAGAACTGGGGCGTACCGTTGATGATCGGATGTCAGAGTTAGCTGACGCGGAAGAGATTTCG
CTCGATGACCTATAA

Structures

Toxin

• AlphaFold DB: A0A249QBN7