Detailed information of TA system TA066879

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 1321060..1321811
• Replicon: chromosome
• Accession: NZ_CP017481
• Organism: Pectobacterium polaris strain NIBIO1006

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: BJJ97_RS05970
• Protein ID: WP_095993370.1
• Coordinates: 1321329..1321811 (+)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: BJJ97_RS05965
• Protein ID: WP_125460916.1
• Coordinates: 1321060..1321338 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJJ97_RS05930	1317147..1317599	+	453	WP_095995325.1	transmembrane HD family hydrolase	-
BJJ97_RS05935	1317602..1318144	+	543	WP_095993364.1	ImmA/IrrE family metallo-endopeptidase	-
BJJ97_RS05940	1318149..1319180	+	1032	WP_095993365.1	beta family protein	-
BJJ97_RS05945	1319163..1319789	-	627	WP_095993366.1	sce7726 family protein	-
BJJ97_RS05950	1319889..1320080	-	192	WP_048263132.1	toxin-antitoxin system HicB family antitoxin	-
BJJ97_RS05955	1320211..1320429	+	219	WP_095993367.1	SymE family type I addiction module toxin	-
BJJ97_RS05960	1320533..1320949	+	417	WP_095993368.1	hypothetical protein	-
BJJ97_RS05965	1321060..1321338	+	279	WP_125460916.1	DUF1778 domain-containing protein	Antitoxin
BJJ97_RS05970	1321329..1321811	+	483	WP_095993370.1	GNAT family N-acetyltransferase	Toxin
BJJ97_RS05975	1321944..1323278	+	1335	WP_095700951.1	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	-
BJJ97_RS05980	1323351..1324238	+	888	WP_095700950.1	sn-glycerol-3-phosphate ABC transporter permease UgpA	-
BJJ97_RS05985	1324264..1325109	+	846	WP_095995326.1	sn-glycerol-3-phosphate ABC transporter permease UgpE	-
BJJ97_RS05990	1325308..1326381	+	1074	WP_095993371.1	sn-glycerol-3-phosphate import ATP-binding protein UgpC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (39-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-92)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 17509.30 Da
• Isoelectric Point: 9.0439

>T66879 WP_095993370.1 NZ_CP017481:1321329-1321811 [Pectobacterium polaris]
MGITAPEPLSSGHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICTEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI

Nucleotide

• Length: 483 bp

>T66879 NZ_CP017481:1321329-1321811 [Pectobacterium polaris]
ATGGGAATAACTGCACCAGAGCCATTATCCTCCGGCCATAATCTTGCTGAATTTTGCAGCCAAGAACCGAGTTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATTTCCCGTGTATATGTTATTTGCACTGAAGGCACCCATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACAGCGCCTGGTGCATATAGGCGTAATGCCCCC
GAATCACTACCAGTCATTGTCCTTGGGCGGCTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTGGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCTCTGGATGAGA
ACGTGCGCAATTTCTATCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCCCTGATGCTACTCTATCCAATTAAAATT
TAG

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10639.11 Da
• Isoelectric Point: 4.4356

>AT66879 WP_125460916.1 NZ_CP017481:1321060-1321338 [Pectobacterium polaris]
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLTELDAPITAERQAR
INDLMSRKSPWE

Nucleotide

• Length: 279 bp

>AT66879 NZ_CP017481:1321060-1321338 [Pectobacterium polaris]
ATGAAACCTGAAACCAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAGCGGGACTTGATCGATATGGCTGCAAA
CCTTGTATCAAAATCACGTACCGATTTTATGCTTGAAGCCGCCTGTCGCGAGGCGCAGGACATCTTGTTGGATCAACGTT
TGTTTATTTTGGACAACGAACAGTTTGACGAATTTTTGACCGAGTTGGATGCACCTATCACTGCAGAGCGTCAGGCTCGC
ATTAACGATCTGATGAGCCGTAAATCTCCATGGGAATAA