Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tsbAT/- |
Location | 1144923..1145728 | Replicon | chromosome |
Accession | NZ_CP017459 | ||
Organism | Staphylococcus nepalensis strain JS9 |
Toxin (Protein)
Gene name | tsbT | Uniprot ID | - |
Locus tag | BJG88_RS05460 | Protein ID | WP_096808992.1 |
Coordinates | 1145546..1145728 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | tsbA | Uniprot ID | - |
Locus tag | BJG88_RS05455 | Protein ID | WP_096808990.1 |
Coordinates | 1144923..1145522 (+) | Length | 200 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BJG88_RS05435 | 1140795..1142258 | + | 1464 | WP_108909268.1 | ABC transporter substrate-binding protein/permease | - |
BJG88_RS05440 | 1142251..1142973 | + | 723 | WP_096808984.1 | amino acid ABC transporter ATP-binding protein | - |
BJG88_RS05445 | 1143138..1144265 | + | 1128 | WP_096808986.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
BJG88_RS05450 | 1144270..1144740 | + | 471 | WP_096808988.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
BJG88_RS05455 | 1144923..1145522 | + | 600 | WP_096808990.1 | glucosamine-6-phosphate isomerase | Antitoxin |
BJG88_RS05460 | 1145546..1145728 | + | 183 | WP_096808992.1 | hypothetical protein | Toxin |
BJG88_RS05465 | 1145932..1146345 | + | 414 | WP_096808994.1 | hypothetical protein | - |
BJG88_RS05470 | 1146556..1147941 | + | 1386 | WP_096808996.1 | class II fumarate hydratase | - |
BJG88_RS05475 | 1148201..1149028 | - | 828 | WP_096808998.1 | RluA family pseudouridine synthase | - |
BJG88_RS05480 | 1149226..1150335 | + | 1110 | WP_096809000.1 | GAF domain-containing sensor histidine kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6910.28 Da Isoelectric Point: 3.8145
>T66830 WP_096808992.1 NZ_CP017459:1145546-1145728 [Staphylococcus nepalensis]
MRNDSTKNQLNHDTEVENEMVDGFEDVVELGKEMEQISEENDEDKLDKAHDASVRSDLDD
MRNDSTKNQLNHDTEVENEMVDGFEDVVELGKEMEQISEENDEDKLDKAHDASVRSDLDD
Download Length: 183 bp
>T66830 NZ_CP017459:1145546-1145728 [Staphylococcus nepalensis]
ATGAGAAATGATAGTACTAAAAACCAATTAAATCATGATACTGAAGTAGAAAATGAAATGGTTGATGGTTTTGAAGATGT
TGTAGAGTTAGGTAAAGAAATGGAACAAATTTCTGAAGAAAACGACGAAGATAAGCTAGATAAAGCACATGATGCAAGCG
TGCGTTCAGATTTAGATGATTAA
ATGAGAAATGATAGTACTAAAAACCAATTAAATCATGATACTGAAGTAGAAAATGAAATGGTTGATGGTTTTGAAGATGT
TGTAGAGTTAGGTAAAGAAATGGAACAAATTTCTGAAGAAAACGACGAAGATAAGCTAGATAAAGCACATGATGCAAGCG
TGCGTTCAGATTTAGATGATTAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22323.12 Da Isoelectric Point: 4.9602
>AT66830 WP_096808990.1 NZ_CP017459:1144923-1145522 [Staphylococcus nepalensis]
MAMNFKVLENERIVAEYAADILRKQFNNNPTTIAGVHLSNDNAPVLDELKKNIDNNAVDFSQINILDYDSNKSYFEALGV
PEGQIYGISYGEDTESFISDKIKTKENKGKLITQILSIDTNSRLNVSINHGLFSAREVILVITGSEKKNIVHKLYEENGK
TSFEPADLKAHRMVNVILDEAAAEGLPEDVRHYFTARFA
MAMNFKVLENERIVAEYAADILRKQFNNNPTTIAGVHLSNDNAPVLDELKKNIDNNAVDFSQINILDYDSNKSYFEALGV
PEGQIYGISYGEDTESFISDKIKTKENKGKLITQILSIDTNSRLNVSINHGLFSAREVILVITGSEKKNIVHKLYEENGK
TSFEPADLKAHRMVNVILDEAAAEGLPEDVRHYFTARFA
Download Length: 600 bp
>AT66830 NZ_CP017459:1144923-1145522 [Staphylococcus nepalensis]
ATGGCAATGAACTTTAAAGTTTTAGAAAATGAAAGAATCGTAGCAGAATATGCTGCTGATATTTTAAGAAAACAATTTAA
CAATAATCCAACAACTATTGCTGGTGTGCACCTTTCTAATGATAATGCACCAGTATTAGATGAACTAAAGAAAAATATAG
ATAATAATGCTGTAGATTTTAGTCAAATTAATATATTAGACTATGACAGTAATAAGTCATATTTTGAAGCATTAGGTGTA
CCAGAAGGCCAAATTTACGGTATTTCTTATGGCGAAGACACAGAATCATTTATAAGTGACAAGATTAAAACTAAAGAAAA
TAAAGGTAAATTGATTACGCAAATACTTTCTATTGATACAAATAGTCGACTTAATGTAAGTATTAATCATGGTCTGTTTT
CTGCAAGAGAAGTTATATTGGTCATTACTGGTAGTGAGAAAAAAAATATTGTTCATAAATTATACGAAGAAAATGGTAAG
ACTTCATTTGAACCCGCTGATTTAAAAGCGCATCGCATGGTTAATGTTATTTTGGATGAAGCAGCTGCAGAAGGTCTGCC
AGAAGATGTTCGTCACTATTTCACTGCACGTTTTGCATAA
ATGGCAATGAACTTTAAAGTTTTAGAAAATGAAAGAATCGTAGCAGAATATGCTGCTGATATTTTAAGAAAACAATTTAA
CAATAATCCAACAACTATTGCTGGTGTGCACCTTTCTAATGATAATGCACCAGTATTAGATGAACTAAAGAAAAATATAG
ATAATAATGCTGTAGATTTTAGTCAAATTAATATATTAGACTATGACAGTAATAAGTCATATTTTGAAGCATTAGGTGTA
CCAGAAGGCCAAATTTACGGTATTTCTTATGGCGAAGACACAGAATCATTTATAAGTGACAAGATTAAAACTAAAGAAAA
TAAAGGTAAATTGATTACGCAAATACTTTCTATTGATACAAATAGTCGACTTAATGTAAGTATTAATCATGGTCTGTTTT
CTGCAAGAGAAGTTATATTGGTCATTACTGGTAGTGAGAAAAAAAATATTGTTCATAAATTATACGAAGAAAATGGTAAG
ACTTCATTTGAACCCGCTGATTTAAAAGCGCATCGCATGGTTAATGTTATTTTGGATGAAGCAGCTGCAGAAGGTCTGCC
AGAAGATGTTCGTCACTATTTCACTGCACGTTTTGCATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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