Detailed information of TA system TA066819

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 2015677..2016355
• Replicon: chromosome
• Accession: NZ_CP017454
• Organism: Dickeya solani strain PPO 9019

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: BJJ98_RS08765
• Protein ID: WP_023637601.1
• Coordinates: 2015677..2016108 (-)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2K8QSU7
• Locus tag: BJJ98_RS08770
• Protein ID: WP_023637600.1
• Coordinates: 2016089..2016355 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJJ98_RS08745	2011646..2012353	-	708	WP_022632172.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
BJJ98_RS08750	2012443..2013342	-	900	WP_022632171.1	site-specific tyrosine recombinase XerD	-
BJJ98_RS08755	2013605..2014930	+	1326	WP_022632170.1	MHS family MFS transporter	-
BJJ98_RS08760	2015059..2015577	+	519	WP_022632169.1	flavodoxin FldB	-
BJJ98_RS08765	2015677..2016108	-	432	WP_023637601.1	protein YgfX	Toxin
BJJ98_RS08770	2016089..2016355	-	267	WP_023637600.1	FAD assembly factor SdhE	Antitoxin
BJJ98_RS08775	2016662..2017642	+	981	WP_022632166.1	tRNA-modifying protein YgfZ	-
BJJ98_RS08780	2017716..2018366	-	651	WP_022632165.1	hemolysin III family protein	-
BJJ98_RS08785	2018576..2019184	+	609	WP_022632164.1	HD domain-containing protein	-
BJJ98_RS08790	2019255..2019905	-	651	WP_022632163.1	LysE family translocator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16808.51 Da
• Isoelectric Point: 11.7737

>T66819 WP_023637601.1 NZ_CP017454:c2016108-2015677 [Dickeya solani]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Nucleotide

• Length: 432 bp

>T66819 NZ_CP017454:c2016108-2015677 [Dickeya solani]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGCATGCAGTTGTTTTCGCTGCTGACGCACGGGTTTCTGGTGCT
GATGATCCTGCTGGCGCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGTTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATTAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGCCCGGCGACCGTGGGTGATGCGCAACGGCGTGTTGCTGTCGTTGCGGGCGACGACTGGCAAAGGGCA
TCAGCGTCTGTGGCTGGCGTCAGACAGTATGGGCAATGAAGAGTGGCGGCTGTTGCGCCAGCTGTTGCAGCAGCACCCGC
TGCAGGGAACGGAATCTTCCCGCCATCATTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10544.03 Da
• Isoelectric Point: 5.5535

>AT66819 WP_023637600.1 NZ_CP017454:c2016355-2016089 [Dickeya solani]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT66819 NZ_CP017454:c2016355-2016089 [Dickeya solani]
ATGGACATCAATAACAAATCACGTATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCATTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGCTGATGAACCATGGCGAGCCGGTGGATCCGGAGCTGAAACGTATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Structures

Antitoxin

• AlphaFold DB: A0A2K8QSU7