66805

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 33153..33748 Replicon chromosome
Accession NZ_CP017454
Organism Dickeya solani strain PPO 9019

Toxin (Protein)


Gene name doc Uniprot ID E0SEA8
Locus tag BJJ98_RS00135 Protein ID WP_013318177.1
Coordinates 33371..33748 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A2K8VUJ6
Locus tag BJJ98_RS00130 Protein ID WP_022633800.1
Coordinates 33153..33374 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ98_RS00110 29554..30273 + 720 WP_022633804.1 nitrate reductase molybdenum cofactor assembly chaperone -
BJJ98_RS00115 30273..30950 + 678 WP_022633803.1 respiratory nitrate reductase subunit gamma -
BJJ98_RS00120 31022..31582 - 561 WP_026594485.1 NUDIX domain-containing protein -
BJJ98_RS00125 31864..33012 + 1149 WP_022633801.1 L-threonine dehydrogenase -
BJJ98_RS00130 33153..33374 + 222 WP_022633800.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BJJ98_RS00135 33371..33748 + 378 WP_013318177.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
BJJ98_RS00140 34386..35564 + 1179 WP_022633799.1 hypothetical protein -
BJJ98_RS00145 35554..37320 + 1767 WP_022633798.1 ATP-binding protein -
BJJ98_RS00150 37402..37584 - 183 WP_072142890.1 hypothetical protein -
BJJ98_RS00155 37816..38082 - 267 WP_022633797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(2-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14320.39 Da        Isoelectric Point: 4.9309

>T66805 WP_013318177.1 NZ_CP017454:33371-33748 [Dickeya solani]
MKWVSAQDVIDFHDRILQVLPGVVGMADPGRAEELIYRVQNRLYYEGVTELFELAATYWVTIARGHIFNDGNKRTAFFVT
MTFLRRNGILIVDNDNSLEELTIKAATGECLVSELAEQLRQRVEK

Download         Length: 378 bp

>T66805 NZ_CP017454:33371-33748 [Dickeya solani]
ATGAAATGGGTGAGTGCGCAGGACGTCATTGACTTCCATGATCGTATTTTGCAGGTGTTGCCTGGTGTGGTGGGTATGGC
TGATCCGGGTCGGGCTGAGGAGTTGATTTATCGAGTACAAAACCGTCTTTATTATGAAGGTGTGACCGAACTGTTTGAGT
TGGCGGCGACGTATTGGGTAACTATTGCTCGTGGTCATATTTTTAATGATGGCAATAAACGCACTGCTTTTTTTGTTACC
ATGACATTTTTGCGCCGCAATGGCATATTGATTGTCGATAACGATAATTCGCTGGAAGAACTCACCATTAAGGCGGCAAC
CGGAGAATGCCTGGTGTCGGAACTCGCCGAACAATTAAGACAACGGGTGGAAAAATAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8207.33 Da        Isoelectric Point: 7.2021

>AT66805 WP_022633800.1 NZ_CP017454:33153-33374 [Dickeya solani]
MKTYTITEARQNIATVIDTAASGEPVEIKRRDGTSAVLIPKAEFEAYQKARLDAEFDFIMQRHGHTIKALADR

Download         Length: 222 bp

>AT66805 NZ_CP017454:33153-33374 [Dickeya solani]
ATGAAGACTTATACCATTACTGAAGCCCGGCAAAATATTGCGACAGTCATTGATACGGCGGCCAGCGGTGAGCCGGTAGA
GATTAAGCGTCGGGATGGCACCTCGGCTGTACTCATCCCCAAAGCAGAGTTTGAGGCTTATCAGAAAGCCAGATTAGACG
CTGAATTCGATTTCATCATGCAGCGCCACGGACACACAATCAAAGCGCTCGCCGACAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E0SEA8

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8VUJ6

References