66799

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1534260..1534885 Replicon chromosome
Accession NZ_CP017453
Organism Dickeya solani D s0432-1

Toxin (Protein)


Gene name Hha Uniprot ID A0A2K8W3K4
Locus tag BJD21_RS06625 Protein ID WP_022632574.1
Coordinates 1534682..1534885 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A2K8W3I1
Locus tag BJD21_RS06620 Protein ID WP_022632575.1
Coordinates 1534260..1534628 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD21_RS06605 1530019..1533165 + 3147 WP_022632578.1 multidrug efflux RND transporter permease subunit -
BJD21_RS06610 1533342..1533593 + 252 WP_022632577.1 type B 50S ribosomal protein L31 -
BJD21_RS06615 1533609..1533752 + 144 WP_022632576.1 type B 50S ribosomal protein L36 -
BJD21_RS06620 1534260..1534628 + 369 WP_022632575.1 Hha toxicity modulator TomB Antitoxin
BJD21_RS06625 1534682..1534885 + 204 WP_022632574.1 hemolysin expression modulator Hha Toxin
BJD21_RS06635 1535446..1535775 + 330 WP_022632573.1 MGMT family protein -
BJD21_RS06640 1535804..1536361 - 558 WP_022632572.1 YbaY family lipoprotein -
BJD21_RS06645 1536613..1537476 + 864 WP_022632571.1 acyl-CoA thioesterase II -
BJD21_RS06650 1537572..1538864 - 1293 WP_022632570.1 ammonium transporter AmtB -
BJD21_RS06655 1538907..1539245 - 339 WP_002208627.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8161.52 Da        Isoelectric Point: 8.8580

>T66799 WP_022632574.1 NZ_CP017453:1534682-1534885 [Dickeya solani D s0432-1]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T66799 NZ_CP017453:1534682-1534885 [Dickeya solani D s0432-1]
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGCACAACCATCGACACGCTTGAGCGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGATGAGCTTGAAATGTTCTATTCAGCTGCAGATCACCGCCTGGCAGAGCTGACGATGAATAAGC
TTTACGACAAAGTACCGACTGCTGTGTGGAGATACGTTCGCTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14223.06 Da        Isoelectric Point: 5.1663

>AT66799 WP_022632575.1 NZ_CP017453:1534260-1534628 [Dickeya solani D s0432-1]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSHGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDTELRKWQKSKSQLFRMFSEKSICTVVKT

Download         Length: 369 bp

>AT66799 NZ_CP017453:1534260-1534628 [Dickeya solani D s0432-1]
ATGGATGAGTACACACCCCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGACAGCAGTCATGGCTGGGTGAATGATCCGACCTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAGC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATACCCGCATGAAGCGGCGCTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGCAATTACGGTATCAATGACACCGAGTTGCGGAAATGGCAAAAATCCAAGTCACAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W3K4

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W3I1

References