Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1072412..1073192 Replicon chromosome
Accession NZ_CP017453
Organism Dickeya solani D s0432-1

Toxin (Protein)


Gene name dhiT Uniprot ID A0A2K8W4P2
Locus tag BJD21_RS04730 Protein ID WP_022632927.1
Coordinates 1072935..1073192 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID A0A2K8W4X0
Locus tag BJD21_RS04725 Protein ID WP_022632928.1
Coordinates 1072412..1072927 (-) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD21_RS04700 1068353..1070080 + 1728 WP_022632933.1 hydrogenase large subunit -
BJD21_RS04705 1070091..1070660 + 570 WP_022632932.1 hydrogenase 4 subunit H -
BJD21_RS04710 1070657..1071448 + 792 WP_022632931.1 NADH-quinone oxidoreductase subunit B family protein -
BJD21_RS04715 1071445..1071843 + 399 WP_022632930.1 formate hydrogenlyase maturation HycH family protein -
BJD21_RS04720 1071836..1072333 + 498 WP_022632929.1 hydrogenase maturation peptidase HycI -
BJD21_RS04725 1072412..1072927 - 516 WP_022632928.1 DUF2442 domain-containing protein Antitoxin
BJD21_RS04730 1072935..1073192 - 258 WP_022632927.1 DUF4160 domain-containing protein Toxin
BJD21_RS04735 1073705..1074247 + 543 WP_022632926.1 4Fe-4S dicluster domain-containing protein -
BJD21_RS04740 1074282..1076432 + 2151 WP_022632925.1 formate dehydrogenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(80-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10007.56 Da        Isoelectric Point: 8.1243

>T66798 WP_022632927.1 NZ_CP017453:c1073192-1072935 [Dickeya solani D s0432-1]
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

>T66798 NZ_CP017453:c1073192-1072935 [Dickeya solani D s0432-1]
ATGCCTGAGGTTGATAGACTGGCAGGGCTAATTTTCCATTTGTACTTTTATGATGATGAGCGGCACTACTTGCCGCATGT
ACATGTCTGCTACGGCAACCATGAGCTGATCATCAGTATTCGTACTGGAACCGAGATCGAAGGATATCTGCCGAATAACA
AGCGCAAGATGGCGCTTGCGCATATCAGGGCCCATCGGGAACAACTGCTGAGTATGTGGGAACGGGCGGTAGTGGGGAGA
AATCCAGGAAAATTGTGA

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19099.82 Da        Isoelectric Point: 5.2747

>AT66798 WP_022632928.1 NZ_CP017453:c1072927-1072412 [Dickeya solani D s0432-1]
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE

Download         Length: 516 bp

>AT66798 NZ_CP017453:c1072927-1072412 [Dickeya solani D s0432-1]
ATGCATAAAATCGTGGAAGTTGACGTTATTGGTGATTTTTCGTTGCGCCTGACCTATGACGATGGTCTGGTTTGCGACAT
TAATCTTTATCAATATGCGTCCAGCCCAGTATTTTCGGACGTCAGCCTATTTATCAAGTTTGGGTTGTTGCCGGATGGCG
CGTTGGAATGGCTGCCGGATATTAAGATTTCCGCGTCAGAATTGCGGAAAAAAGGGGAGTATGTCAGCCACACGCTGGCG
GTGCGAGAAAGGCACTTCGCCGATGTCATCTCGCGCGCCTTCTATGATGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
AGCAGCGTTGAAAATCGCGGTGGAAAAACATGGCAACAGCACCGTAGCCAAAGAGGCGGGGGCGAAAAGTCGCACCAGCT
TGTATAAGTCGCTGAATAAAAATACCCATGTCAGCCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAGTTGGAA
GAGTTGCAATTGGAAGATCTGCAATTGGAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W4P2

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W4X0

References