Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 5346040..5346818 | Replicon | chromosome |
Accession | NZ_CP017450 | ||
Organism | Klebsiella sp. LTGPAF-6F |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | A0A1D8JZH2 |
Locus tag | BJF97_RS25005 | Protein ID | WP_032692863.1 |
Coordinates | 5346040..5346528 (-) | Length | 163 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | A0A1D8JZH7 |
Locus tag | BJF97_RS25010 | Protein ID | WP_032692864.1 |
Coordinates | 5346525..5346818 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BJF97_RS24990 | 5341563..5343473 | + | 1911 | WP_032692860.1 | hypothetical protein | - |
BJF97_RS24995 | 5343470..5345170 | + | 1701 | WP_032692861.1 | hypothetical protein | - |
BJF97_RS25000 | 5345277..5345975 | - | 699 | WP_032692862.1 | hypothetical protein | - |
BJF97_RS25005 | 5346040..5346528 | - | 489 | WP_032692863.1 | GNAT family N-acetyltransferase | Toxin |
BJF97_RS25010 | 5346525..5346818 | - | 294 | WP_032692864.1 | DUF1778 domain-containing protein | Antitoxin |
BJF97_RS25015 | 5347197..5348585 | - | 1389 | WP_032692865.1 | DASS family sodium-coupled anion symporter | - |
BJF97_RS34835 | 5348781..5348957 | - | 177 | WP_177341169.1 | hypothetical protein | - |
BJF97_RS25020 | 5349131..5350501 | + | 1371 | WP_025105933.1 | cystathionine beta-synthase | - |
BJF97_RS25025 | 5350512..5351657 | + | 1146 | WP_004854188.1 | PLP-dependent aspartate aminotransferase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 163 a.a. Molecular weight: 17694.67 Da Isoelectric Point: 8.1567
>T66778 WP_032692863.1 NZ_CP017450:c5346528-5346040 [Klebsiella sp. LTGPAF-6F]
MISTPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCHDAKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDRSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSNEAREFYLRVGFEPSLIDPMMLMVTLGDLVE
SI
MISTPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCHDAKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDRSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSNEAREFYLRVGFEPSLIDPMMLMVTLGDLVE
SI
Download Length: 489 bp
>T66778 NZ_CP017450:c5346528-5346040 [Klebsiella sp. LTGPAF-6F]
ATGATCTCCACACCAGAGCCGCTTCATGCCGGGCACATTCTAACCCCGTTCTGCTGCGGCGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAGAACCAGCTTTCTGGCGCGTCCCGTACGTTTGTCTGCTGCCACGATGCTAAGGTGATGG
CTTACTACTCGCTGGCGTCCAGCGCGGTAACGACAAACACCGCCCCCGGCCGCTTTCGTCGCAATATGCCCGATCCGATC
CCGGTTGTAGTGCTGGGACGTCTGGCGGTGGATCGGTCGCTACATGGACAAGGCGTTGGGCGGGCGCTGGTGAGGGATGC
CGGACTGCGGGTGATTCAGGTGGCGGAAACTATCGGTATTCGCGGGATGCTGGTTCACGCTCTGTCGAATGAAGCGCGGG
AGTTTTACCTGCGCGTGGGGTTCGAGCCATCGCTGATAGATCCGATGATGCTCATGGTGACTTTGGGGGATTTGGTGGAG
AGTATTTAG
ATGATCTCCACACCAGAGCCGCTTCATGCCGGGCACATTCTAACCCCGTTCTGCTGCGGCGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAGAACCAGCTTTCTGGCGCGTCCCGTACGTTTGTCTGCTGCCACGATGCTAAGGTGATGG
CTTACTACTCGCTGGCGTCCAGCGCGGTAACGACAAACACCGCCCCCGGCCGCTTTCGTCGCAATATGCCCGATCCGATC
CCGGTTGTAGTGCTGGGACGTCTGGCGGTGGATCGGTCGCTACATGGACAAGGCGTTGGGCGGGCGCTGGTGAGGGATGC
CGGACTGCGGGTGATTCAGGTGGCGGAAACTATCGGTATTCGCGGGATGCTGGTTCACGCTCTGTCGAATGAAGCGCGGG
AGTTTTACCTGCGCGTGGGGTTCGAGCCATCGCTGATAGATCCGATGATGCTCATGGTGACTTTGGGGGATTTGGTGGAG
AGTATTTAG
Antitoxin
Download Length: 98 a.a. Molecular weight: 10930.56 Da Isoelectric Point: 9.9171
>AT66778 WP_032692864.1 NZ_CP017450:c5346818-5346525 [Klebsiella sp. LTGPAF-6F]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLARLDQAPAPN
AALRKTMQTPAPWEQEK
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLARLDQAPAPN
AALRKTMQTPAPWEQEK
Download Length: 294 bp
>AT66778 NZ_CP017450:c5346818-5346525 [Klebsiella sp. LTGPAF-6F]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAACCTGCGCATCAGGCCCGCTGAGCGCGATCTTATCGA
TCGGGCGGCGAAAGCCAGAGGAAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGCGCTGCTGCCGAGGAAGCGTTGA
TCGAGCAGCGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTTGCCCGTCTGGATCAGGCTCCTGCGCCCAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAACCTGCGCATCAGGCCCGCTGAGCGCGATCTTATCGA
TCGGGCGGCGAAAGCCAGAGGAAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGCGCTGCTGCCGAGGAAGCGTTGA
TCGAGCAGCGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTTGCCCGTCTGGATCAGGCTCCTGCGCCCAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1D8JZH2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1D8JZH7 |