Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 1320056..1320875 Replicon chromosome
Accession NZ_CP017450
Organism Klebsiella sp. LTGPAF-6F

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag BJF97_RS06175 Protein ID WP_004110819.1
Coordinates 1320056..1320313 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A2J5QA69
Locus tag BJF97_RS06180 Protein ID WP_032693191.1
Coordinates 1320324..1320875 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJF97_RS06160 1315732..1316508 - 777 WP_004847986.1 Uxu operon transcriptional regulator -
BJF97_RS06165 1316647..1318122 - 1476 WP_014228053.1 fructuronate reductase -
BJF97_RS06170 1318196..1319380 - 1185 WP_014228054.1 mannonate dehydratase -
BJF97_RS06175 1320056..1320313 + 258 WP_004110819.1 YjhX family toxin Toxin
BJF97_RS06180 1320324..1320875 + 552 WP_032693191.1 N-acetyltransferase Antitoxin
BJF97_RS06185 1320893..1322521 + 1629 WP_032693192.1 SAM-dependent methyltransferase -
BJF97_RS34650 1322555..1322713 + 159 Protein_1193 hypothetical protein -
BJF97_RS06195 1322710..1323125 + 416 Protein_1194 type II toxin-antitoxin system VapC family toxin -
BJF97_RS06200 1323394..1323867 - 474 WP_032693194.1 hypothetical protein -
BJF97_RS06205 1324178..1324951 - 774 WP_088168442.1 Zygote formation protein zyg1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T66766 WP_004110819.1 NZ_CP017450:1320056-1320313 [Klebsiella sp. LTGPAF-6F]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T66766 NZ_CP017450:1320056-1320313 [Klebsiella sp. LTGPAF-6F]
ATGAATCTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCTAAAGGTGGCCGGATCGCGCACATCCGCGATGCATC
AGGCCGCGTCACCTCTGTTGAATGCTACAGCCGCGAAGGGCTCCTGCTCAGCGACTGCACGCTCGCCGTTTTCAAAAAAC
TCAAAACCAAAAAGCTGATTAAGTCCGTCAACGGACAGCCCTACCGCATCAATACCACCGGGCTGAATAACGTCCGCGCA
CAGCTGGACAATCGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20154.00 Da        Isoelectric Point: 6.4903

>AT66766 WP_032693191.1 NZ_CP017450:1320324-1320875 [Klebsiella sp. LTGPAF-6F]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGELIRHGIEQLKAMGSQMVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQRLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT66766 NZ_CP017450:1320324-1320875 [Klebsiella sp. LTGPAF-6F]
ATGACAAACCATAGCTTCACTTTTCATGTCGCCTCTGAAGGCGATACCGATGACATTCTCGACGTCGAAACCCGGGCTTT
CGGCTACAGCAAAGAGGCCAGGCTGGTGGCCGATTTGCTCAACGATGAGAGCGCCTGCCCGACGCTATCGCTGCTGGCCA
GGCATAACGGAGAGGCGGTTGGGCATATTTTATTCACCCGGGCGACGTTCAAAGGGGAGCCGGACTCGCCGATGATGCAC
ATCCTTGCTCCCCTGGCGGTGGTGCCGGAATACCAGGGCGTGGGCGTTGGCGGAGAGCTTATCCGGCACGGCATTGAGCA
GTTGAAAGCAATGGGAAGCCAGATGGTATTTGTTCTGGGCCACGCCGCTTACTACCCCAGGCACGGGTTTGAGCCATGCG
CGGGAGATAAAGGCTATCCGGCGCCTTATCCGATTCCGGAGGCGCATAAAGCCTGCTGGATGCTGCAGCGGCTTTCGTCT
CAGCCTCTGGGACGAACGGGCCAGATACAGTGCGCCCGGGCGTTAATGAAACCCGAGCACTGGCGCGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure
AlphaFold DB A0A2J5QA69

References