Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2234266..2234537 Replicon chromosome
Accession NZ_CP017446
Organism Escherichia coli O157:H7 strain 9234

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2234396..2234499 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2234266..2234537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4C47_RS11445 2230821..2231483 - 663 WP_000944243.1 exodeoxyribonuclease X -
A4C47_RS11450 2231507..2232163 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
A4C47_RS11455 2232265..2232495 - 231 WP_000916763.1 DNA polymerase III subunit theta -
A4C47_RS11460 2232634..2233008 + 375 WP_000168751.1 CopC domain-containing protein YobA -
A4C47_RS11465 2233012..2233884 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
A4C47_RS11470 2233897..2234238 + 342 WP_000976483.1 YebY family protein -
- 2234266..2234537 - 272 - - Antitoxin
- 2234396..2234499 + 104 - - Toxin
A4C47_RS11480 2234634..2235290 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
A4C47_RS11485 2235291..2235482 - 192 WP_001296140.1 YebW family protein -
A4C47_RS11490 2235587..2235823 - 237 WP_001295499.1 DUF1480 family protein -
A4C47_RS11495 2235941..2237380 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T66737 NZ_CP017446:2234396-2234499 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT66737 NZ_CP017446:c2234537-2234266 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References