Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2235324..2235595 | Replicon | chromosome |
| Accession | NZ_CP017436 | ||
| Organism | Escherichia coli O157:H7 strain 2149 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2235454..2235557 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2235324..2235595 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A4C44_RS11450 | 2231879..2232541 | - | 663 | WP_000944243.1 | exodeoxyribonuclease X | - |
| A4C44_RS11455 | 2232565..2233221 | - | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| A4C44_RS11460 | 2233323..2233553 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| A4C44_RS11465 | 2233692..2234066 | + | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| A4C44_RS11470 | 2234070..2234942 | + | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| A4C44_RS11475 | 2234955..2235296 | + | 342 | WP_000976483.1 | YebY family protein | - |
| - | 2235324..2235595 | - | 272 | - | - | Antitoxin |
| - | 2235454..2235557 | + | 104 | - | - | Toxin |
| A4C44_RS11485 | 2235692..2236348 | + | 657 | WP_000812736.1 | protein-serine/threonine phosphatase | - |
| A4C44_RS11490 | 2236349..2236540 | - | 192 | WP_001296140.1 | YebW family protein | - |
| A4C44_RS11495 | 2236645..2236881 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| A4C44_RS11500 | 2236999..2238438 | - | 1440 | WP_001302304.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T66567 NZ_CP017436:2235454-2235557 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT66567 NZ_CP017436:c2235595-2235324 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
