Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1504644..1505145 Replicon chromosome
Accession NZ_CP017415
Organism Acidihalobacter yilgarnenesis strain F5

Toxin (Protein)


Gene name relE Uniprot ID A0A1D8IMU1
Locus tag BI364_RS07205 Protein ID WP_070078165.1
Coordinates 1504891..1505145 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1D8IMT2
Locus tag BI364_RS07200 Protein ID WP_070078164.1
Coordinates 1504644..1504901 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI364_RS07190 1499660..1502299 - 2640 WP_156782652.1 EAL domain-containing protein -
BI364_RS17300 1502413..1502604 - 192 Protein_1425 IS3 family transposase -
BI364_RS07195 1502863..1504488 + 1626 WP_070078163.1 methyl-accepting chemotaxis protein -
BI364_RS07200 1504644..1504901 + 258 WP_070078164.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BI364_RS07205 1504891..1505145 + 255 WP_070078165.1 Txe/YoeB family addiction module toxin Toxin
BI364_RS07210 1505201..1505485 + 285 WP_070078166.1 integration host factor subunit beta -
BI364_RS07215 1505783..1506076 - 294 WP_197495929.1 type II toxin-antitoxin system VapC family toxin -
BI364_RS07220 1506533..1507291 - 759 WP_070078167.1 IS21-like element helper ATPase IstB -
BI364_RS07225 1507323..1508855 - 1533 WP_083251223.1 IS21 family transposase -
BI364_RS17310 1509092..1509280 + 189 WP_197495931.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10004.44 Da        Isoelectric Point: 9.5464

>T66502 WP_070078165.1 NZ_CP017415:1504891-1505145 [Acidihalobacter yilgarnenesis]
MPIKFSDEAWEDYLFWQANDKAVLKRINRLIQAIQRSPFEGIGKPEALRHNLSGFWSRRINDEHRLVYAIQGNSILIAQC
RYHY

Download         Length: 255 bp

>T66502 NZ_CP017415:1504891-1505145 [Acidihalobacter yilgarnenesis]
ATGCCGATTAAATTCTCCGATGAGGCTTGGGAGGACTACCTGTTCTGGCAGGCAAACGACAAAGCCGTTCTTAAGCGCAT
TAACCGATTGATTCAGGCGATTCAGCGTTCGCCTTTCGAGGGGATTGGGAAACCCGAGGCGCTAAGGCATAATCTCTCTG
GGTTCTGGTCACGTCGGATCAACGATGAGCATCGTCTTGTCTATGCCATCCAGGGAAATTCGATATTGATCGCCCAGTGT
CGCTATCATTACTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9554.92 Da        Isoelectric Point: 8.5162

>AT66502 WP_070078164.1 NZ_CP017415:1504644-1504901 [Acidihalobacter yilgarnenesis]
MDAITYSYTRQHLAKVMNQVDDDRTPVLITRQNGKPVVMMSLQDFNALEETAYLMRSPRNAKRLLASIEQLATNGGKARS
LVDAD

Download         Length: 258 bp

>AT66502 NZ_CP017415:1504644-1504901 [Acidihalobacter yilgarnenesis]
ATGGACGCTATCACCTACAGCTATACCCGCCAGCATTTGGCGAAGGTCATGAATCAAGTTGACGATGATCGCACGCCTGT
ACTGATTACACGCCAGAACGGAAAGCCCGTGGTGATGATGTCACTGCAGGACTTTAACGCGCTGGAAGAAACCGCCTATC
TGATGCGTAGCCCAAGAAACGCCAAACGTTTGTTAGCCTCCATAGAACAACTGGCCACCAATGGAGGGAAGGCAAGAAGC
CTCGTCGATGCCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D8IMU1

Antitoxin

Source ID Structure
AlphaFold DB A0A1D8IMT2

References