Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4591732..4592098 Replicon chromosome
Accession NZ_CP017323
Organism Xanthomonas campestris pv. campestris str. CN15

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCCCN15_RS20715 Protein ID WP_011270059.1
Coordinates 4591732..4591866 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCCCN15_RS20720 Protein ID WP_011038999.1
Coordinates 4591946..4592098 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN15_RS20695 4586995..4588647 - 1653 WP_052844768.1 M28 family peptidase -
XCCCN15_RS20700 4588812..4589756 - 945 WP_040942012.1 MBL fold metallo-hydrolase -
XCCCN15_RS20705 4589840..4591129 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
XCCCN15_RS20710 4591289..4591498 - 210 WP_011038998.1 CsbD family protein -
XCCCN15_RS20715 4591732..4591866 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCCCN15_RS20720 4591946..4592098 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCCCN15_RS20725 4592209..4593132 - 924 WP_040942405.1 arginase -
XCCCN15_RS20730 4593446..4593907 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
XCCCN15_RS20735 4593990..4594349 + 360 WP_040942013.1 hypothetical protein -
XCCCN15_RS20740 4594452..4595369 + 918 WP_012439506.1 hypothetical protein -
XCCCN15_RS20745 4595366..4595908 + 543 WP_012439507.1 GTPase -
XCCCN15_RS20750 4596243..4596926 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T66482 WP_011270059.1 NZ_CP017323:c4591866-4591732 [Xanthomonas campestris pv. campestris str. CN15]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66482 NZ_CP017323:c4591866-4591732 [Xanthomonas campestris pv. campestris str. CN15]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT66482 WP_011038999.1 NZ_CP017323:c4592098-4591946 [Xanthomonas campestris pv. campestris str. CN15]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT66482 NZ_CP017323:c4592098-4591946 [Xanthomonas campestris pv. campestris str. CN15]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References