Detailed information of TA system TA066481

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1239396..1240174
• Replicon: chromosome
• Accession: NZ_CP017323
• Organism: Xanthomonas campestris pv. campestris str. CN15

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: -
• Locus tag: XCCCN15_RS05355
• Protein ID: WP_040940794.1
• Coordinates: 1239396..1239887 (-)
• Length: 164 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: Q8P668
• Locus tag: XCCCN15_RS05360
• Protein ID: WP_011038219.1
• Coordinates: 1239884..1240174 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XCCCN15_RS05340	1235724..1236599	+	876	WP_011038222.1	30S ribosomal protein S6--L-glutamate ligase	-
XCCCN15_RS05345	1237249..1237926	+	678	WP_003490678.1	response regulator transcription factor	-
XCCCN15_RS05350	1237919..1239253	+	1335	WP_040940793.1	HAMP domain-containing histidine kinase	-
XCCCN15_RS05355	1239396..1239887	-	492	WP_040940794.1	GNAT family N-acetyltransferase	Toxin
XCCCN15_RS05360	1239884..1240174	-	291	WP_011038219.1	DUF1778 domain-containing protein	Antitoxin
XCCCN15_RS05365	1240249..1240650	-	402	WP_040940795.1	type I toxin-antitoxin system SymE family toxin	-
XCCCN15_RS05375	1241182..1241805	-	624	WP_040940796.1	dephospho-CoA kinase	-
XCCCN15_RS05380	1241819..1242682	-	864	WP_040940797.1	A24 family peptidase	-
XCCCN15_RS05385	1242689..1243951	-	1263	WP_040940798.1	type II secretion system F family protein	-
XCCCN15_RS05390	1244303..1244701	+	399	WP_040940799.1	pilin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (21-142)

Antitoxin

• Vibrio phage ICP1, Orf50 (1-95)

Sequences

Toxin

Protein

• Length: 164 a.a.
• Molecular weight: 17560.25 Da
• Isoelectric Point: 7.9507

>T66481 WP_040940794.1 NZ_CP017323:c1239887-1239396 [Xanthomonas campestris pv. campestris str. CN15]
MTVSAPEPLTAHHRVEPLASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGCEPSPLDPMVLVVTLEDLK
ASL

Nucleotide

• Length: 492 bp

>T66481 NZ_CP017323:c1239887-1239396 [Xanthomonas campestris pv. campestris str. CN15]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTAGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCCTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTGCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10678.23 Da
• Isoelectric Point: 10.5480

>AT66481 WP_011038219.1 NZ_CP017323:c1240174-1239884 [Xanthomonas campestris pv. campestris str. CN15]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Nucleotide

• Length: 291 bp

>AT66481 NZ_CP017323:c1240174-1239884 [Xanthomonas campestris pv. campestris str. CN15]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Structures

Antitoxin

• AlphaFold DB: Q8P668