66480

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4629082..4629448 Replicon chromosome
Accession NZ_CP017319
Organism Xanthomonas campestris pv. campestris str. CN18

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag BIU85_RS20930 Protein ID WP_011270059.1
Coordinates 4629082..4629216 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag BIU85_RS20935 Protein ID WP_011038999.1
Coordinates 4629296..4629448 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BIU85_RS20910 4624345..4625997 - 1653 WP_162808741.1 M28 family peptidase -
BIU85_RS20915 4626162..4627106 - 945 WP_187305905.1 MBL fold metallo-hydrolase -
BIU85_RS20920 4627190..4628479 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
BIU85_RS20925 4628639..4628848 - 210 WP_011038998.1 CsbD family protein -
BIU85_RS20930 4629082..4629216 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
BIU85_RS20935 4629296..4629448 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
BIU85_RS20940 4629559..4630482 - 924 WP_040942405.1 arginase -
BIU85_RS20945 4630796..4631257 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
BIU85_RS20950 4631340..4631699 + 360 WP_011039002.1 hypothetical protein -
BIU85_RS20955 4631802..4632719 + 918 WP_075286290.1 hypothetical protein -
BIU85_RS20960 4632716..4633258 + 543 WP_075286291.1 GTPase -
BIU85_RS20965 4633593..4634276 + 684 WP_070693788.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T66480 WP_011270059.1 NZ_CP017319:c4629216-4629082 [Xanthomonas campestris pv. campestris str. CN18]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66480 NZ_CP017319:c4629216-4629082 [Xanthomonas campestris pv. campestris str. CN18]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT66480 WP_011038999.1 NZ_CP017319:c4629448-4629296 [Xanthomonas campestris pv. campestris str. CN18]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT66480 NZ_CP017319:c4629448-4629296 [Xanthomonas campestris pv. campestris str. CN18]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References