Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 898073..899580 Replicon chromosome
Accession NZ_CP017311
Organism Hydrogenophaga sp. PBC

Toxin (Protein)


Gene name rlegT Uniprot ID A0A1L1PAK9
Locus tag Q5W_RS04385 Protein ID WP_009519805.1
Coordinates 898073..898984 (-) Length 304 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A1L1PR13
Locus tag Q5W_RS04390 Protein ID WP_009519804.1
Coordinates 898981..899580 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Q5W_RS04360 893918..894400 + 483 WP_009519810.1 flavin reductase family protein -
Q5W_RS04365 894417..894785 + 369 WP_009519809.1 VOC family protein -
Q5W_RS04370 894782..895864 + 1083 WP_009519808.1 LLM class flavin-dependent oxidoreductase -
Q5W_RS04375 895910..896878 + 969 WP_069902748.1 tripartite tricarboxylate transporter substrate binding protein -
Q5W_RS04380 896862..897842 + 981 WP_009519806.1 alpha/beta hydrolase fold domain-containing protein -
Q5W_RS04385 898073..898984 - 912 WP_009519805.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Q5W_RS04390 898981..899580 - 600 WP_009519804.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
Q5W_RS04395 899773..900255 + 483 WP_009519803.1 hypothetical protein -
Q5W_RS04400 900404..901969 + 1566 WP_050980711.1 recombinase family protein -
Q5W_RS04405 901966..902865 + 900 WP_009519801.1 ParB/RepB/Spo0J family partition protein -
Q5W_RS04410 902862..903746 + 885 WP_009519800.1 ParB N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-264)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-52)


Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 34033.16 Da        Isoelectric Point: 6.2837

>T66463 WP_009519805.1 NZ_CP017311:c898984-898073 [Hydrogenophaga sp. PBC]
MNQRNVAASVRARLLNKARAEKLDFNLLLTRYALERMLYRLSVSEQRGQFLLKGALLFDLWFDLPHRPTHDADLLGFGST
DIPYLEKLFREISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCPVQIDIGFGDAVTPAPENVQYPVIL
DGMPQPQLRVYPRYTVVAEKLEAIVKLGILNSRMKDYFDLWVLARHSDFNGAVLAQAIRATFERRGTAIPSSAPLGLTDE
FGLDEQKARQWQAFLRKNTLEPMPLATVIVVLREFLLPVLTALTADEGFDRQWRAGAGWDGNE

Download         Length: 912 bp

>T66463 NZ_CP017311:c898984-898073 [Hydrogenophaga sp. PBC]
ATGAACCAGCGCAACGTCGCCGCGTCGGTTCGTGCCCGGCTGCTCAACAAGGCTCGTGCCGAAAAACTCGACTTCAACCT
GCTACTGACCCGCTATGCGCTGGAGCGGATGCTGTACCGCCTGAGTGTCTCGGAGCAGCGCGGGCAATTCCTGCTCAAAG
GCGCGCTGCTGTTCGACCTCTGGTTCGACCTGCCGCATCGTCCGACGCACGATGCCGACCTGCTGGGTTTTGGTTCAACC
GATATTCCGTATCTGGAAAAGCTGTTCCGCGAGATCAGCCAGATCGCCAGCGATGACGGCATCGTGTTTCAGGCTGACAG
CGTGAAGGCCGCCGAAATCCGCAAGGAGGCGAACTACGCGGGTGTCCGGGTGACGATGATCGGCCTGCTCGACGGCGCGC
GCTGTCCGGTGCAGATCGACATCGGCTTCGGCGACGCCGTCACGCCCGCACCGGAGAACGTGCAGTACCCGGTCATCCTC
GATGGCATGCCGCAGCCGCAACTGCGGGTCTATCCTCGCTACACCGTCGTCGCCGAAAAGCTGGAGGCGATAGTCAAGCT
CGGTATCCTCAACAGCCGGATGAAGGACTACTTCGACCTGTGGGTTCTGGCCCGGCATTCCGACTTCAACGGCGCGGTGC
TGGCGCAGGCGATTCGCGCCACGTTCGAGCGCCGGGGCACGGCCATCCCGTCCAGCGCACCGCTGGGCCTCACCGACGAG
TTCGGTCTAGACGAGCAGAAGGCCAGGCAGTGGCAGGCGTTCCTGCGCAAGAACACCCTGGAGCCGATGCCGCTGGCCAC
GGTGATCGTGGTGCTGCGCGAATTCCTGCTGCCGGTGCTGACGGCGCTCACTGCGGACGAAGGTTTCGACCGTCAGTGGC
GCGCGGGCGCAGGCTGGGACGGGAACGAGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 21941.52 Da        Isoelectric Point: 10.0961

>AT66463 WP_009519804.1 NZ_CP017311:c899580-898981 [Hydrogenophaga sp. PBC]
MDTTADKLLELVRAQGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLAARPVSAHGTLAEVARRVPKGVVCLLSA
LRFHDLTTQAPFEVWLAIDNKAATPKLDYPPLRLVRFSGAALTEGVEEHVVDGVTVRVTGVAKTVADCFKYRNKIGLDVA
LEALRDAWNGKRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT66463 NZ_CP017311:c899580-898981 [Hydrogenophaga sp. PBC]
ATGGACACGACCGCCGACAAGCTGCTGGAACTGGTGCGCGCGCAGGGACTGCTGCGCCCGCACGATCTGGCTCCGCTGGG
CATCCCACGGGTGGCCCTGACGCGGGCGGTGCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTCGCGG
CGCGTCCGGTGTCGGCACACGGCACGCTGGCCGAGGTCGCCCGCCGCGTGCCCAAGGGCGTGGTGTGCCTGCTGTCGGCG
CTGCGCTTCCACGACCTGACGACGCAGGCCCCTTTCGAGGTCTGGCTGGCCATCGACAACAAGGCGGCCACGCCAAAGCT
GGACTACCCGCCGCTGCGCCTCGTGCGCTTCTCCGGCGCGGCGCTGACCGAGGGCGTGGAGGAACACGTCGTCGATGGCG
TCACCGTCCGCGTCACGGGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCCTCGACGTGGCT
CTGGAGGCGCTGCGCGATGCGTGGAACGGCAAGCGCATGACCAGCGATGAAATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L1PAK9

Antitoxin

Source ID Structure
AlphaFold DB A0A1L1PR13

References