66460

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 416537..416903 Replicon chromosome
Accession NZ_CP017310
Organism Xanthomonas campestris pv. campestris str. CN12

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCCCN12_RS01875 Protein ID WP_011270059.1
Coordinates 416769..416903 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCCCN12_RS01870 Protein ID WP_011038999.1
Coordinates 416537..416689 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN12_RS01840 411709..412392 - 684 WP_070693788.1 dTMP kinase -
XCCCN12_RS01845 412727..413269 - 543 WP_075286291.1 GTPase -
XCCCN12_RS01850 413266..414183 - 918 WP_075286290.1 hypothetical protein -
XCCCN12_RS01855 414286..414645 - 360 WP_011039002.1 hypothetical protein -
XCCCN12_RS01860 414728..415189 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
XCCCN12_RS01865 415503..416426 + 924 WP_040942405.1 arginase -
XCCCN12_RS01870 416537..416689 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCCCN12_RS01875 416769..416903 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCCCN12_RS01880 417137..417346 + 210 WP_011038998.1 CsbD family protein -
XCCCN12_RS01885 417506..418795 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
XCCCN12_RS01890 418879..419823 + 945 WP_187305905.1 MBL fold metallo-hydrolase -
XCCCN12_RS01895 419988..421640 + 1653 WP_162808741.1 M28 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T66460 WP_011270059.1 NZ_CP017310:416769-416903 [Xanthomonas campestris pv. campestris str. CN12]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66460 NZ_CP017310:416769-416903 [Xanthomonas campestris pv. campestris str. CN12]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT66460 WP_011038999.1 NZ_CP017310:416537-416689 [Xanthomonas campestris pv. campestris str. CN12]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT66460 NZ_CP017310:416537-416689 [Xanthomonas campestris pv. campestris str. CN12]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References