66459

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4601344..4601707 Replicon chromosome
Accession NZ_CP017308
Organism Xanthomonas campestris pv. campestris str. CN03

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCCCN03_RS20830 Protein ID WP_011270059.1
Coordinates 4601344..4601478 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCCCN03_RS20835 Protein ID WP_011038999.1
Coordinates 4601555..4601707 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN03_RS20810 4596608..4598260 - 1653 WP_043890286.1 M28 family peptidase -
XCCCN03_RS20815 4598425..4599369 - 945 WP_207206363.1 MBL fold metallo-hydrolase -
XCCCN03_RS20820 4599453..4600742 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
XCCCN03_RS20825 4600902..4601111 - 210 WP_011038998.1 CsbD family protein -
XCCCN03_RS20830 4601344..4601478 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCCCN03_RS20835 4601555..4601707 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCCCN03_RS20840 4601818..4602741 - 924 WP_103700858.1 arginase -
XCCCN03_RS20845 4603055..4603516 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
XCCCN03_RS20850 4603599..4603958 + 360 WP_011039002.1 hypothetical protein -
XCCCN03_RS20855 4604061..4604978 + 918 WP_014506231.1 hypothetical protein -
XCCCN03_RS20860 4604975..4605517 + 543 WP_068574727.1 GTPase -
XCCCN03_RS20865 4605853..4606536 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T66459 WP_011270059.1 NZ_CP017308:c4601478-4601344 [Xanthomonas campestris pv. campestris str. CN03]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66459 NZ_CP017308:c4601478-4601344 [Xanthomonas campestris pv. campestris str. CN03]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT66459 WP_011038999.1 NZ_CP017308:c4601707-4601555 [Xanthomonas campestris pv. campestris str. CN03]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT66459 NZ_CP017308:c4601707-4601555 [Xanthomonas campestris pv. campestris str. CN03]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTGGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References