Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4616425..4616791 Replicon chromosome
Accession NZ_CP017307
Organism Xanthomonas campestris pv. campestris str. CN17

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCCCN17_RS20705 Protein ID WP_011270059.1
Coordinates 4616425..4616559 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCCCN17_RS20710 Protein ID WP_011038999.1
Coordinates 4616639..4616791 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN17_RS20685 4611688..4613340 - 1653 WP_162808741.1 M28 family peptidase -
XCCCN17_RS20690 4613505..4614449 - 945 WP_187305905.1 MBL fold metallo-hydrolase -
XCCCN17_RS20695 4614533..4615822 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
XCCCN17_RS20700 4615982..4616191 - 210 WP_011038998.1 CsbD family protein -
XCCCN17_RS20705 4616425..4616559 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCCCN17_RS20710 4616639..4616791 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCCCN17_RS20715 4616902..4617825 - 924 WP_040942405.1 arginase -
XCCCN17_RS20720 4618139..4618600 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
XCCCN17_RS20725 4618683..4619042 + 360 WP_011039002.1 hypothetical protein -
XCCCN17_RS20730 4619145..4620062 + 918 WP_075286290.1 hypothetical protein -
XCCCN17_RS20735 4620059..4620601 + 543 WP_075286291.1 GTPase -
XCCCN17_RS20740 4620936..4621619 + 684 WP_070693788.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T66458 WP_011270059.1 NZ_CP017307:c4616559-4616425 [Xanthomonas campestris pv. campestris str. CN17]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66458 NZ_CP017307:c4616559-4616425 [Xanthomonas campestris pv. campestris str. CN17]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT66458 WP_011038999.1 NZ_CP017307:c4616791-4616639 [Xanthomonas campestris pv. campestris str. CN17]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT66458 NZ_CP017307:c4616791-4616639 [Xanthomonas campestris pv. campestris str. CN17]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References