Detailed information of TA system TA066423

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 4029419..4029960
• Replicon: chromosome
• Accession: NZ_CP017290
• Organism: Pseudomonas sp. LPH1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BHQ29_RS18590
• Protein ID: WP_059390424.1
• Coordinates: 4029664..4029960 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BHQ29_RS18585
• Protein ID: WP_021487971.1
• Coordinates: 4029419..4029676 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BHQ29_RS18555	4024992..4025485	+	494	Protein_3665	GNAT family N-acetyltransferase	-
BHQ29_RS18560	4025561..4025839	-	279	WP_072423160.1	DUF465 domain-containing protein	-
BHQ29_RS18565	4025908..4026156	-	249	WP_017678808.1	YdcH family protein	-
BHQ29_RS18570	4026353..4027378	+	1026	WP_074913914.1	DUF21 domain-containing protein	-
BHQ29_RS18575	4027379..4028155	-	777	WP_079784630.1	ferredoxin--NADP reductase	-
BHQ29_RS18580	4028226..4029350	+	1125	WP_079784631.1	class I SAM-dependent methyltransferase	-
BHQ29_RS18585	4029419..4029676	+	258	WP_021487971.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BHQ29_RS18590	4029664..4029960	+	297	WP_059390424.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BHQ29_RS18595	4029964..4031283	-	1320	WP_079784632.1	Zn-dependent protease	-
BHQ29_RS18600	4031283..4032725	-	1443	WP_079784633.1	TldD/PmbA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11450.36 Da
• Isoelectric Point: 6.7178

>T66423 WP_059390424.1 NZ_CP017290:4029664-4029960 [Pseudomonas sp. LPH1]
MAEIVWTNTALEQLDDLAQYIALDKPDAARALVRRVVETVSRLVDFPLSGRVPDELPHSVYREIVVPPCRIFYRYTDTTV
FIIHIMREERVLRAHMLK

Nucleotide

• Length: 297 bp

>T66423 NZ_CP017290:4029664-4029960 [Pseudomonas sp. LPH1]
ATGGCTGAAATAGTCTGGACGAACACCGCCCTCGAGCAGCTCGACGATCTCGCGCAATACATCGCCCTCGACAAACCGGA
TGCCGCGCGAGCACTGGTCAGAAGAGTCGTTGAAACAGTCTCACGGTTAGTGGATTTCCCCCTGTCGGGCCGTGTTCCGG
ATGAGCTTCCACACTCGGTGTACCGCGAAATCGTCGTCCCACCCTGCCGAATTTTCTACCGCTATACAGACACAACGGTT
TTCATCATCCACATCATGCGAGAGGAGCGCGTGCTGCGCGCCCACATGCTCAAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9757.31 Da
• Isoelectric Point: 7.3181

>AT66423 WP_021487971.1 NZ_CP017290:4029419-4029676 [Pseudomonas sp. LPH1]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGNTLNHEQAKERL
SKWLK

Nucleotide

• Length: 258 bp

>AT66423 NZ_CP017290:4029419-4029676 [Pseudomonas sp. LPH1]
ATGAAAGTCGAGTTGGTCACCAACCTGAAGCGACAGGCCACCAAGATTCTGGCCGACCTTCACGAGTCCAAAGAACCTGT
ACTGATCACCGAACATGGGATGCCTTCGGCTTATCTGGTGGATGTCGATGACTACCAGTTCATGCAGAAGCGTCTTGCCC
TTCTGGATGCTCTGGCTCGCGGAGAACGTGCCGTAATCGAGGGCAACACCCTGAACCATGAGCAGGCCAAGGAAAGGCTG
AGCAAATGGCTGAAATAG