Detailed information of TA system TA066420

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2021921..2022415
• Replicon: chromosome
• Accession: NZ_CP017290
• Organism: Pseudomonas sp. LPH1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BHQ29_RS24430
• Protein ID: WP_152030010.1
• Coordinates: 2022176..2022415 (+)
• Length: 80 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BHQ29_RS09300
• Protein ID: WP_079783546.1
• Coordinates: 2021921..2022166 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BHQ29_RS09285	2017236..2018114	+	879	WP_079783544.1	sel1 repeat family protein	-
BHQ29_RS24425	2018189..2019556	+	1368	WP_177345318.1	hypothetical protein	-
BHQ29_RS09295	2019643..2021784	+	2142	WP_079783545.1	hypothetical protein	-
BHQ29_RS09300	2021921..2022166	+	246	WP_079783546.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
BHQ29_RS24430	2022176..2022415	+	240	WP_152030010.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
BHQ29_RS09310	2022822..2023403	-	582	WP_079783547.1	plasmid pRiA4b ORF-3 family protein	-
BHQ29_RS09315	2023417..2024292	-	876	WP_079783548.1	WYL domain-containing protein	-
BHQ29_RS09320	2024428..2026002	+	1575	WP_079785292.1	DNA recombination protein RmuC	-
BHQ29_RS09325	2026026..2026673	+	648	WP_079783549.1	peptidase M15	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2005670..2062855	57185

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-63)

Sequences

Toxin

Protein

• Length: 80 a.a.
• Molecular weight: 8789.50 Da
• Isoelectric Point: 10.8056

>T66420 WP_152030010.1 NZ_CP017290:2022176-2022415 [Pseudomonas sp. LPH1]
MPSALKEWQKLGHTVPGQIKKRNCASAWIIPRFICRGKIKLLASGCLLVCRVEDERVVVVVVAVGKRERGAAYQSAKDR

Nucleotide

• Length: 240 bp

>T66420 NZ_CP017290:2022176-2022415 [Pseudomonas sp. LPH1]
CTGCCCTCCGCCTTGAAGGAGTGGCAGAAGCTCGGCCATACAGTGCCCGGGCAGATCAAAAAAAGAAACTGCGCGAGCGC
CTGGATAATCCCAAGGTTCATATGCCGGGGCAAAATCAAGCTGCTCGCGTCCGGCTGTCTCTTGGTATGTCGCGTCGAAG
ATGAACGCGTGGTGGTCGTGGTGGTTGCCGTTGGCAAGCGCGAGCGCGGGGCCGCTTACCAATCTGCCAAGGACCGTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8814.19 Da
• Isoelectric Point: 4.3611

>AT66420 WP_079783546.1 NZ_CP017290:2021921-2022166 [Pseudomonas sp. LPH1]
MQRILADVAVSVSELKKNPSGILAGAGSRPVAVLNHNRVMGYLVPAEFYEQLMERLDDLELVEVVNALSGEEPIPVRLDG
L

Nucleotide

• Length: 246 bp

>AT66420 NZ_CP017290:2021921-2022166 [Pseudomonas sp. LPH1]
ATGCAGCGCATCTTGGCTGACGTCGCGGTCAGTGTTTCTGAACTGAAGAAAAATCCATCAGGCATCTTGGCTGGCGCTGG
TAGTAGGCCTGTCGCCGTGCTCAATCACAATCGCGTCATGGGATACCTGGTGCCGGCAGAGTTTTATGAGCAACTGATGG
AGCGCCTGGATGATCTGGAGCTGGTCGAAGTGGTGAACGCTCTCTCGGGTGAGGAGCCTATCCCGGTGCGCTTGGATGGG
CTATGA