Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1140529..1141931 Replicon chromosome
Accession NZ_CP017290
Organism Pseudomonas sp. LPH1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag BHQ29_RS05305 Protein ID WP_079783040.1
Coordinates 1140529..1141098 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A2G5FYL1
Locus tag BHQ29_RS05310 Protein ID WP_074917079.1
Coordinates 1141104..1141931 (+) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHQ29_RS05300 1136835..1140323 - 3489 WP_079783039.1 hybrid sensor histidine kinase/response regulator -
BHQ29_RS05305 1140529..1141098 + 570 WP_079783040.1 GNAT family N-acetyltransferase Toxin
BHQ29_RS05310 1141104..1141931 + 828 WP_074917079.1 AraC family transcriptional regulator Antitoxin
BHQ29_RS05315 1142009..1143346 - 1338 WP_079783041.1 peptidase -
BHQ29_RS05320 1143537..1144109 + 573 WP_017675063.1 LemA family protein -
BHQ29_RS05325 1144120..1145025 + 906 WP_074917073.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21467.69 Da        Isoelectric Point: 7.3597

>T66419 WP_079783040.1 NZ_CP017290:1140529-1141098 [Pseudomonas sp. LPH1]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADMREQRALPFVIRLGDELVGTTRFA
DFMNTLPACEIGWTWLDRGQHGSGLNTSIKYLMLKHAFEHWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALREAMEAGFNA

Download         Length: 570 bp

>T66419 NZ_CP017290:1140529-1141098 [Pseudomonas sp. LPH1]
ATGTTCAAGCCGCAGCTGGTGACTTTGCAACGTGGCGCTCTGCGCCTGGAACCGCTCTCTGACGCGGATATCCCCGCGCT
GGTGGCGCTGGCCGAAGCCAATCGCGAGGAGCTGCTGTACATGAGCGGCACCCAGCGACTGGACTGGTACCGCAGCGCCC
TGGCCGATATGCGCGAGCAGCGGGCACTGCCATTCGTCATTCGTCTGGGTGACGAGTTGGTAGGCACCACCCGCTTCGCC
GACTTCATGAACACCCTGCCGGCCTGTGAAATCGGCTGGACCTGGCTCGACCGCGGCCAGCATGGCAGCGGGCTGAACAC
CAGCATCAAGTATTTGATGCTCAAGCACGCTTTCGAACATTGGGGCATGGTTCGCGTGCAACTGAAAACCGCCGCCAGCA
ACCTGCGTTCGCAACGCGCCATCGAGAAGCTTGGCGCCGTTCGTGAAGGGTTGCTGCGCAACCATCGCCGTCTGGCTGAT
GGCCGACTCGATGACACCGTGCTGTACAGCATCACCGATCTGGAATGGCCGGCGCTGCGTGAGGCAATGGAGGCGGGCTT
CAACGCCTGA

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30723.11 Da        Isoelectric Point: 8.7310

>AT66419 WP_074917079.1 NZ_CP017290:1141104-1141931 [Pseudomonas sp. LPH1]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNAQVLGALQELGLAKAGMPSFAFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLVEPPSLEELAAAVSLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp

>AT66419 NZ_CP017290:1141104-1141931 [Pseudomonas sp. LPH1]
ATGCACAGTCGCGAGCAGACCCGCTTCTGGCAAGCTTCCGCATTGAGCGGCGTCGAGCTGTTGCAGGCGCGCTATCTTGA
ACAGCGCTTCGCGCCCCACGTGCATGAAGGTTTCGTGTTCACCGTGATCGAGCATGGCGCACAGCGCTTTCGTCATCGCG
GTTGTGATCATCTGGCACCGCAGGGCAGCATGGTGCTGATCAACCCGGACGAAGTGCACACCGGCTCCAAGGCGCACGAA
GACGGTTGGCGCTATCGCGGTTTCTATCCCGACAACGCCCAGGTACTGGGGGCGCTGCAGGAGCTGGGCCTGGCCAAGGC
TGGCATGCCGTCGTTTGCCTTCAGCGTGCTGCATGATCCACGTTTGCATGCGGCCTTTCTGCAACTGCACCAACTGCTTG
AGGGTGGTGCCGAGGCACTGCAGCAGCAACTGGCCTGGCGTGAGGCGATTCTGCTGCTGTTTCAGCATCATGCGCAGCTT
GCCGAACCACCTGCGCCTGGGCGTGAGCCATGGGCAGTGGCCTGCGCCAAGCAGATGCTTGCCGAACGTCTGGTCGAGCC
GCCGTCTCTGGAAGAGCTGGCGGCTGCGGTTAGCCTCTCTCCTTTTCACTTCGCGCGCGTATTTCGCCGCGCGACCGGCT
TGCCGCCGCATGCCTGGCTCAAGCAGCGTCGCCTGGAACAGGCGCGGGCGTTGCTCAAGACGGGCTGTACGGCGGTCGCT
GTGGCCATGCAGTTGGGCTTCGCCGATCAGAGCCACTTGTCGCGGCAGTTCAAGCAGGTTTATGGCGTGAGCCCTGGCGA
ATATCGCAGCGCGGTTGCAAGAAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2G5FYL1

References