Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3294671..3294942 Replicon chromosome
Accession NZ_CP017249
Organism Escherichia coli strain NADC 5570/86-24/6565 isolate mutant

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3294709..3294812 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3294671..3294942 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHW76_RS17260 3291828..3293267 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BHW76_RS17265 3293385..3293621 + 237 WP_001295499.1 DUF1480 family protein -
BHW76_RS17270 3293726..3293917 + 192 WP_001296140.1 YebW family protein -
BHW76_RS17275 3293918..3294574 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3294671..3294942 + 272 - - Antitoxin
- 3294709..3294812 - 104 - - Toxin
BHW76_RS17285 3294970..3295311 - 342 WP_000976483.1 YebY family protein -
BHW76_RS17290 3295324..3296196 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
BHW76_RS17295 3296200..3296574 - 375 WP_000168751.1 CopC domain-containing protein YobA -
BHW76_RS17300 3296713..3296943 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BHW76_RS17305 3297045..3297701 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
BHW76_RS17310 3297725..3298387 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T66302 NZ_CP017249:c3294812-3294709 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT66302 NZ_CP017249:3294671-3294942 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References