Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 793346..793987 Replicon chromosome
Accession NZ_CP017239
Organism Burkholderia cenocepacia strain CR318

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BHQ31_RS20535 Protein ID WP_078041408.1
Coordinates 793649..793987 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BHQ31_RS20530 Protein ID WP_006490972.1
Coordinates 793346..793645 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHQ31_RS20505 788524..789795 + 1272 WP_078041405.1 Rieske 2Fe-2S domain-containing protein -
BHQ31_RS20510 789810..790286 + 477 WP_006479528.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
BHQ31_RS20515 790322..790648 + 327 WP_006479527.1 non-heme iron oxygenase ferredoxin subunit -
BHQ31_RS20520 790638..791858 + 1221 WP_078041406.1 FAD-dependent oxidoreductase -
BHQ31_RS20525 792011..793297 + 1287 WP_078041407.1 DUF445 domain-containing protein -
BHQ31_RS20530 793346..793645 - 300 WP_006490972.1 putative addiction module antidote protein Antitoxin
BHQ31_RS20535 793649..793987 - 339 WP_078041408.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BHQ31_RS20545 794366..796006 + 1641 WP_078041409.1 acetolactate synthase large subunit -
BHQ31_RS20550 796035..797468 + 1434 WP_006479522.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-109)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12578.44 Da        Isoelectric Point: 9.0259

>T66277 WP_078041408.1 NZ_CP017239:c793987-793649 [Burkholderia cenocepacia]
MVDILQSVPYSAPTFSIRTTDVFEAWFAGLPDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVHYVRRG
TIWVILLCGGDKSTQQADIRAAHAMLAHLDME

Download         Length: 339 bp

>T66277 NZ_CP017239:c793987-793649 [Burkholderia cenocepacia]
ATGGTTGACATCCTGCAATCCGTGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGACGTCTTCGAAGCGTGGTT
CGCCGGCCTGCCGGATCGCGTCGCGCGGCGGCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCCGGGCGACT
GGAAATCCGCCGGCTCCCCCGTCGTCGAAATGCGTATCGACCACGGCCCCGGCTATCGCGTCCATTACGTGAGGCGCGGA
ACGATATGGGTCATCCTGCTCTGCGGCGGCGATAAATCGACGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGC
GCACCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10608.04 Da        Isoelectric Point: 6.4771

>AT66277 WP_006490972.1 NZ_CP017239:c793645-793346 [Burkholderia cenocepacia]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAAA

Download         Length: 300 bp

>AT66277 NZ_CP017239:c793645-793346 [Burkholderia cenocepacia]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
CTGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGTGCCCGCGGCATGTCGC
AGGTCGCACGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References