66273

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3320071..3321791 Replicon chromosome
Accession NZ_CP017236
Organism Yersinia ruckeri strain QMA0440 isolate 14/0165-5k

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag QMA0440_RS15570 Protein ID WP_038245758.1
Coordinates 3321135..3321791 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag QMA0440_RS15565 Protein ID WP_038245756.1
Coordinates 3320071..3321138 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMA0440_RS15525 3316376..3316660 - 285 WP_038245319.1 antirestriction protein -
QMA0440_RS15530 3317010..3317959 - 950 Protein_2965 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
QMA0440_RS15535 3317952..3318347 - 396 WP_038245317.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
QMA0440_RS15540 3318422..3318652 - 231 WP_080717349.1 DUF4942 domain-containing protein -
QMA0440_RS18270 3318802..3318930 + 129 Protein_2968 helix-turn-helix domain-containing protein -
QMA0440_RS15545 3318954..3319043 + 90 Protein_2969 transposase -
QMA0440_RS15550 3319072..3319362 - 291 Protein_2970 transposase -
QMA0440_RS15555 3319367..3319765 + 399 Protein_2971 DDE-type integrase/transposase/recombinase -
QMA0440_RS15560 3319784..3320050 - 267 Protein_2972 hypothetical protein -
QMA0440_RS15565 3320071..3321138 - 1068 WP_038245756.1 macro domain-containing protein Antitoxin
QMA0440_RS15570 3321135..3321791 - 657 WP_038245758.1 DUF4433 domain-containing protein Toxin
QMA0440_RS15575 3321794..3322369 - 576 WP_038245760.1 DUF4433 domain-containing protein -
QMA0440_RS15580 3322416..3322883 - 468 WP_051847072.1 restriction endonuclease subunit S -
QMA0440_RS15585 3323147..3323437 - 291 WP_038245762.1 type II toxin-antitoxin system RelE/ParE family toxin -
QMA0440_RS15590 3323427..3323681 - 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
QMA0440_RS15595 3323855..3324307 - 453 Protein_2979 site-specific integrase -
QMA0440_RS15600 3324355..3324663 - 309 WP_038245765.1 hypothetical protein -
QMA0440_RS15605 3324739..3325650 - 912 WP_080717354.1 toll/interleukin-1 receptor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3320071..3326840 6769
- flank IS/Tn - - 3319072..3319320 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25244.74 Da        Isoelectric Point: 6.6007

>T66273 WP_038245758.1 NZ_CP017236:c3321791-3321135 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLTNYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

>T66273 NZ_CP017236:c3321791-3321135 [Yersinia ruckeri]
GTGGCCTATGACTACAGCACTAGCCTCAACCCGGAAAAAGCCTTGATCTGGCGCATTGTCCATCGGGACAATATTCCGTG
GATACTGGACAACGGTCTGCACTGTGGCAACAGTCCGGTGCAGGCGGAAGACTGGATTAATATCGGTAACCCGGAGCTTA
TCGACAAACGTGCCGGACATCTGGTGCCAACCGGAATGCGGGGGACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATCCGCAGCGGACGTGGCGGCATTAAGCAACGCCCCAATGAGGAGATCGTTATTCTGGT
CAGTAGCCTGCGAAACATGGTGGCGCAAAATGTTTCCTTCGTGTTTACCGATAGCCACGCATATTATAACCTTACTAATT
ACTTTACCGAGCTGGACAGTCTGAACCAGATCGATTGGCCCATTCTACAAGCGCGGGATTTCCGTCGCGATCAGGACGAT
TTGGCCAAGTTCGAACGCTATCAGGCAGAGGCGTTAATTTGGAAGCACTGCCCAATAGCGCTGCTTGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGTTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCGCGGGCTG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40846.27 Da        Isoelectric Point: 6.6976

>AT66273 WP_038245756.1 NZ_CP017236:c3321138-3320071 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIKEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp

>AT66273 NZ_CP017236:c3321138-3320071 [Yersinia ruckeri]
ATGATTACATTTACACAAGGCAATTTACTGGATGCGCCCGTAGAAGCACTAGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCGTCAATATGAAAGCCTATGCTCTCGCCTGCAAACATAAGC
AGGTAATGACAGGTAAAATGTTTATTACCGAAACCGGCGAACTGATGGGGCCTCGCTGGATTGTCAACTTCCCAACTAAA
CAACACTGGCGCGCAGACTCCCGCATGGAGTGGGTTGAAGACGGCTTGCAGGATTTACGCCGCTTTTTGATCAAAGAGAA
AGTGCAATCTATCGCCATTCCCCCACTGGGGGCGGGTAACGGCGGCCTGAATTGGTCGGACGTTCGGATGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATTCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACTCCCGCCAGAGCGCTGATTGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCATCAGCAGGAAGATGTGCTGAAACTGC
GGTTTGAGGCGCACTATTACGGCCCCTACGCCCCCAACCTTAACCATCTGCTTAACGCGCTAGATGGCACGTATCTGAAA
GCAGAGAAACGCATCCCGGACACCCAGCCGCTGGATGTGATCTGGTTTAATGATCAGGAAAAAGAACACATCAACCTCTG
GCTGAACAACGAGGCCAAAGAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCAACCGTTGACTGGCTGCTGACCCGAGGAAAATGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTGCACCAGTGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAGAATCTGCAATTTGCCAT
CAACCGCGTGATGGAGTTCCATTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References