Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 17496..18018 Replicon plasmid pFORC51
Accession NZ_CP017233
Organism Salmonella enterica strain FORC_051

Toxin (Protein)


Gene name relE Uniprot ID D0QMR1
Locus tag FORC51_RS23950 Protein ID WP_000220561.1
Coordinates 17737..18018 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag FORC51_RS23945 Protein ID WP_000121743.1
Coordinates 17496..17747 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC51_RS23925 13766..14119 - 354 WP_024156393.1 hypothetical protein -
FORC51_RS23930 14256..14702 - 447 WP_001074378.1 hypothetical protein -
FORC51_RS23935 14706..15557 - 852 WP_000435059.1 replication initiation protein -
FORC51_RS23940 15562..16431 - 870 WP_001212191.1 replication initiation protein -
FORC51_RS23945 17496..17747 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
FORC51_RS23950 17737..18018 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC51_RS23955 18368..18883 + 516 WP_001025387.1 J domain-containing protein -
FORC51_RS23960 18957..19505 + 549 WP_001178641.1 hypothetical protein -
FORC51_RS23965 19571..19783 + 213 WP_001446884.1 hypothetical protein -
FORC51_RS23970 19773..20015 + 243 WP_000008708.1 hypothetical protein -
FORC51_RS23975 20109..20438 + 330 WP_000866654.1 hypothetical protein -
FORC51_RS23980 20481..20660 + 180 WP_000439079.1 hypothetical protein -
FORC51_RS23990 20893..21165 + 273 WP_000167280.1 hypothetical protein -
FORC51_RS23995 21491..22036 + 546 WP_000757692.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..96999 96999


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T66258 WP_000220561.1 NZ_CP017233:17737-18018 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T66258 NZ_CP017233:17737-18018 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT66258 WP_000121743.1 NZ_CP017233:17496-17747 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT66258 NZ_CP017233:17496-17747 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5I302

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References