Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3592796..3593343 Replicon chromosome
Accession NZ_CP017190
Organism Xanthomonas campestris pv. vesicatoria str. 85-10

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2W0H9
Locus tag BHE83_RS15205 Protein ID WP_039418332.1
Coordinates 3593041..3593343 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag BHE83_RS15200 Protein ID WP_008574056.1
Coordinates 3592796..3593053 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHE83_RS15185 3587935..3589398 - 1464 WP_011345812.1 ribonuclease H-like domain-containing protein -
BHE83_RS15190 3589395..3591890 - 2496 WP_011345813.1 DEAD/DEAH box helicase -
BHE83_RS15195 3592068..3592730 + 663 WP_011345814.1 hemolysin III family protein -
BHE83_RS15200 3592796..3593053 + 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BHE83_RS15205 3593041..3593343 + 303 WP_039418332.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BHE83_RS15215 3593526..3594425 - 900 WP_011345816.1 SDR family NAD(P)-dependent oxidoreductase -
BHE83_RS15220 3594485..3595222 - 738 WP_008574050.1 SDR family oxidoreductase -
BHE83_RS24800 3595347..3595490 + 144 Protein_2970 LysR family transcriptional regulator -
BHE83_RS24805 3596417..3597982 + 1566 WP_011345818.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11523.36 Da        Isoelectric Point: 9.0231

>T66219 WP_039418332.1 NZ_CP017190:3593041-3593343 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T66219 NZ_CP017190:3593041-3593343 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCGGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTTGAGCAATTAATTGAACACCCCGACAGCGGAAGCCGGC
CACAGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT66219 WP_008574056.1 NZ_CP017190:3592796-3593053 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp

>AT66219 NZ_CP017190:3592796-3593053 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W0H9

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References