Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
Location | 3592796..3593343 | Replicon | chromosome |
Accession | NZ_CP017190 | ||
Organism | Xanthomonas campestris pv. vesicatoria str. 85-10 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A3G2W0H9 |
Locus tag | BHE83_RS15205 | Protein ID | WP_039418332.1 |
Coordinates | 3593041..3593343 (+) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q3BZM5 |
Locus tag | BHE83_RS15200 | Protein ID | WP_008574056.1 |
Coordinates | 3592796..3593053 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BHE83_RS15185 | 3587935..3589398 | - | 1464 | WP_011345812.1 | ribonuclease H-like domain-containing protein | - |
BHE83_RS15190 | 3589395..3591890 | - | 2496 | WP_011345813.1 | DEAD/DEAH box helicase | - |
BHE83_RS15195 | 3592068..3592730 | + | 663 | WP_011345814.1 | hemolysin III family protein | - |
BHE83_RS15200 | 3592796..3593053 | + | 258 | WP_008574056.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
BHE83_RS15205 | 3593041..3593343 | + | 303 | WP_039418332.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BHE83_RS15215 | 3593526..3594425 | - | 900 | WP_011345816.1 | SDR family NAD(P)-dependent oxidoreductase | - |
BHE83_RS15220 | 3594485..3595222 | - | 738 | WP_008574050.1 | SDR family oxidoreductase | - |
BHE83_RS24800 | 3595347..3595490 | + | 144 | Protein_2970 | LysR family transcriptional regulator | - |
BHE83_RS24805 | 3596417..3597982 | + | 1566 | WP_011345818.1 | ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11523.36 Da Isoelectric Point: 9.0231
>T66219 WP_039418332.1 NZ_CP017190:3593041-3593343 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR
Download Length: 303 bp
>T66219 NZ_CP017190:3593041-3593343 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCGGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTTGAGCAATTAATTGAACACCCCGACAGCGGAAGCCGGC
CACAGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCGGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTTGAGCAATTAATTGAACACCCCGACAGCGGAAGCCGGC
CACAGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9686.18 Da Isoelectric Point: 10.0780
>AT66219 WP_008574056.1 NZ_CP017190:3592796-3593053 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK
Download Length: 258 bp
>AT66219 NZ_CP017190:3592796-3593053 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2W0H9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2WGS6 |