Detailed information of TA system TA066218

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 3448567..3450146
• Replicon: chromosome
• Accession: NZ_CP017190
• Organism: Xanthomonas campestris pv. vesicatoria str. 85-10

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: BHE83_RS14630
• Protein ID: WP_129111554.1
• Coordinates: 3448567..3449832 (+)
• Length: 422 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: Q3BM53
• Locus tag: BHE83_RS14635
• Protein ID: WP_011349168.1
• Coordinates: 3449850..3450146 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BHE83_RS14620	3444364..3445914	+	1551	WP_170808575.1	hypothetical protein	-
BHE83_RS24745	3446266..3447116	+	851	Protein_2850	hypothetical protein	-
BHE83_RS14625	3447583..3448419	+	837	Protein_2851	restriction endonuclease	-
BHE83_RS14630	3448567..3449832	+	1266	WP_129111554.1	zeta toxin family protein	Toxin
BHE83_RS14635	3449850..3450146	+	297	WP_011349168.1	hypothetical protein	Antitoxin
BHE83_RS14640	3450669..3451078	+	410	Protein_2854	hypothetical protein	-
BHE83_RS14645	3451248..3451724	-	477	WP_011349170.1	nuclear transport factor 2 family protein	-
BHE83_RS14650	3451788..3452357	-	570	WP_011349171.1	TetR/AcrR family transcriptional regulator	-
BHE83_RS14655	3452474..3453046	-	573	WP_041855097.1	TetR/AcrR family transcriptional regulator	-
BHE83_RS14660	3453130..3453870	+	741	WP_011349173.1	glucose 1-dehydrogenase	-
BHE83_RS14665	3454236..3454754	-	519	WP_041855098.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3430627..3455060	24433

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (151-291)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 422 a.a.
• Molecular weight: 45183.56 Da
• Isoelectric Point: 6.1927

>T66218 WP_129111554.1 NZ_CP017190:3448567-3449832 [Xanthomonas campestris pv. vesicatoria str. 85-10]
IKNKIGIAGTAGLFTSHVPFDDAESKGVQAESSQAAPEYKFQTQLDNLPARPASSKSSNTTHAYVHASPPHSVPIAGAST
AAVTHQQATQLKGTDELYGLGNLPSSGPGRWEYLANPENWHPERRKLHEKLLDEARSSALTLAESLERDGCQPTLFALRG
NTATGKTRIATKKIPALAAALEKTGGKGCINPDVFKSSLAKSEAGAKIFSSAQVHNESCFLADHFEDGLRSQRTGSGAIA
SIVVDKRLARAYEIDSYIELAKETGRKVELCDIDAPLENSLTGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMSVIDRFI
ADPSLGNYRLFGTAEDGKKVMVASVMGGELSVEDADLYEKITSPQSSVTGDLADKIIDNELIDRLTNNIDDPERAANTRA
ALEKYNGKSWSAALAAHSELI

Nucleotide

• Length: 1266 bp

>T66218 NZ_CP017190:3448567-3449832 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATAAAAAACAAGATAGGCATTGCTGGCACAGCCGGGCTTTTTACTTCTCATGTTCCTTTCGATGACGCAGAATCCAAAGG
CGTCCAAGCTGAGTCATCACAAGCGGCGCCGGAGTATAAATTCCAGACCCAGCTTGATAATTTGCCAGCTAGACCCGCTA
GTTCGAAGAGCAGCAACACCACTCATGCTTATGTTCATGCATCGCCGCCGCATTCGGTGCCGATCGCAGGTGCATCGACC
GCCGCGGTGACACATCAACAGGCTACTCAGCTTAAAGGCACCGATGAGTTATATGGTTTGGGCAACCTCCCATCTTCTGG
TCCGGGGCGATGGGAGTATCTGGCGAATCCGGAGAACTGGCATCCGGAGCGCCGTAAGTTGCACGAAAAGCTATTAGATG
AAGCACGATCTTCGGCCTTGACCCTGGCAGAATCTCTTGAGCGCGATGGCTGCCAACCGACATTGTTTGCGTTGCGCGGA
AACACTGCCACGGGTAAGACGCGGATAGCCACAAAAAAAATTCCAGCTCTCGCCGCAGCTCTGGAGAAGACAGGTGGGAA
AGGTTGCATCAATCCAGATGTATTCAAGAGTTCGCTTGCGAAGTCGGAGGCCGGCGCCAAGATATTTAGCTCGGCGCAAG
TTCATAACGAATCATGTTTTCTTGCTGACCATTTTGAAGACGGGCTTCGCTCTCAAAGGACGGGCAGCGGTGCAATCGCT
AGCATTGTTGTCGACAAGCGCTTGGCAAGGGCGTACGAAATCGACAGCTATATAGAACTAGCCAAAGAAACAGGTCGAAA
AGTTGAATTGTGCGATATCGATGCACCCCTTGAGAATTCTTTGACGGGAGTTTTGCAACGGAAACCTGAAGGTGAAGATC
CTAGGCCTCCTTACCCTGTAGTCTCGAGTGGATTTGTGGCCGTACGAAGCAATAGAATGAGTGTGATAGACAGGTTCATC
GCCGATCCGAGCCTGGGAAACTATCGACTATTCGGAACAGCCGAGGATGGTAAGAAGGTCATGGTTGCTAGCGTCATGGG
CGGTGAGTTGAGTGTAGAGGATGCTGATTTATATGAAAAGATAACGTCCCCGCAGTCCTCGGTTACCGGTGATTTGGCTG
ATAAGATAATCGACAATGAATTGATTGATCGTCTGACAAATAATATAGATGATCCCGAGCGCGCGGCGAATACGCGAGCC
GCGCTGGAAAAATATAACGGCAAGTCGTGGTCGGCCGCGCTAGCTGCTCATAGCGAGCTAATTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11347.05 Da
• Isoelectric Point: 8.0069

>AT66218 WP_011349168.1 NZ_CP017190:3449850-3450146 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKTLKGAEALEFHKKLKGRNEALHASDIASALVRADAVGKERFDLEELEKLCYTSSAGRLTDVKERRDIYERMYYVEYPK
IMTLKEFARIVETLSSWS

Nucleotide

• Length: 297 bp

>AT66218 NZ_CP017190:3449850-3450146 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAAACTTTGAAAGGCGCAGAGGCGCTCGAATTCCATAAGAAGCTTAAGGGACGCAATGAAGCCTTACATGCTTCCGA
TATCGCGTCAGCATTAGTACGCGCCGATGCCGTCGGCAAGGAACGGTTTGATCTCGAGGAACTGGAAAAACTTTGCTATA
CCAGTAGTGCGGGGCGCCTTACTGATGTGAAAGAGCGCCGCGACATATATGAGCGGATGTACTACGTCGAGTATCCTAAA
ATTATGACGTTAAAGGAATTTGCTCGTATCGTTGAGACACTTTCCTCTTGGTCATGA

Structures

Antitoxin

• AlphaFold DB: Q3BM53