66217

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 3042190..3042551 Replicon chromosome
Accession NZ_CP017190
Organism Xanthomonas campestris pv. vesicatoria str. 85-10

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BHE83_RS13020 Protein ID WP_005914328.1
Coordinates 3042190..3042324 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q3BN31
Locus tag BHE83_RS13025 Protein ID WP_011348912.1
Coordinates 3042399..3042551 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHE83_RS13005 3039224..3040246 - 1023 WP_011348910.1 MBL fold metallo-hydrolase -
BHE83_RS13010 3040297..3041586 - 1290 WP_011348911.1 tryptophan--tRNA ligase -
BHE83_RS13015 3041753..3041962 - 210 WP_003486601.1 CsbD family protein -
BHE83_RS13020 3042190..3042324 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BHE83_RS13025 3042399..3042551 - 153 WP_011348912.1 entericidin A/B family lipoprotein Antitoxin
BHE83_RS13030 3042658..3043581 - 924 WP_008576436.1 arginase -
BHE83_RS13035 3043902..3044354 + 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
BHE83_RS13040 3044418..3044777 + 360 WP_003486613.1 hypothetical protein -
BHE83_RS13045 3044874..3045791 + 918 WP_008576439.1 hypothetical protein -
BHE83_RS13050 3045788..3046330 + 543 WP_039418666.1 GTPase -
BHE83_RS13055 3046801..3047481 + 681 WP_011348915.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T66217 WP_005914328.1 NZ_CP017190:c3042324-3042190 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66217 NZ_CP017190:c3042324-3042190 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCGGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5123.06 Da        Isoelectric Point: 8.2782

>AT66217 WP_011348912.1 NZ_CP017190:c3042551-3042399 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT66217 NZ_CP017190:c3042551-3042399 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCAGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3G2W7I0

References