66215

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4879273..4879634 Replicon chromosome
Accession NZ_CP017188
Organism Xanthomonas citri pv. glycines str. 8ra

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BHE84_RS22290 Protein ID WP_005914328.1
Coordinates 4879273..4879407 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BHE84_RS22295 Protein ID WP_003486606.1
Coordinates 4879482..4879634 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHE84_RS22270 4874424..4876115 - 1692 WP_016850771.1 M20/M25/M40 family metallo-hydrolase -
BHE84_RS22275 4876307..4877341 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
BHE84_RS22280 4877380..4878669 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
BHE84_RS22285 4878837..4879046 - 210 WP_003486601.1 CsbD family protein -
BHE84_RS22290 4879273..4879407 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BHE84_RS22295 4879482..4879634 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BHE84_RS22300 4879741..4880664 - 924 WP_003486608.1 arginase -
BHE84_RS22305 4880985..4881437 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BHE84_RS22310 4881501..4881860 + 360 WP_003486613.1 hypothetical protein -
BHE84_RS22315 4881957..4882874 + 918 WP_016850774.1 hypothetical protein -
BHE84_RS22320 4882871..4883413 + 543 WP_003486615.1 GTPase -
BHE84_RS22330 4883851..4884534 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T66215 WP_005914328.1 NZ_CP017188:c4879407-4879273 [Xanthomonas citri pv. glycines str. 8ra]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T66215 NZ_CP017188:c4879407-4879273 [Xanthomonas citri pv. glycines str. 8ra]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT66215 WP_003486606.1 NZ_CP017188:c4879634-4879482 [Xanthomonas citri pv. glycines str. 8ra]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT66215 NZ_CP017188:c4879634-4879482 [Xanthomonas citri pv. glycines str. 8ra]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References