Detailed information of TA system TA066214

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 99317..99861
• Replicon: chromosome
• Accession: NZ_CP017188
• Organism: Xanthomonas citri pv. glycines str. 8ra

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BHE84_RS00445
• Protein ID: WP_005928957.1
• Coordinates: 99562..99861 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1D9ED60
• Locus tag: BHE84_RS00440
• Protein ID: WP_016849693.1
• Coordinates: 99317..99574 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BHE84_RS00425	94436..95917	-	1482	WP_033483017.1	ribonuclease H-like domain-containing protein	-
BHE84_RS00430	95914..98409	-	2496	WP_016849694.1	DEAD/DEAH box helicase	-
BHE84_RS00435	98587..99249	+	663	WP_005912558.1	hemolysin III family protein	-
BHE84_RS00440	99317..99574	+	258	WP_016849693.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BHE84_RS00445	99562..99861	+	300	WP_005928957.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BHE84_RS00455	100049..100947	-	899	Protein_84	SDR family NAD(P)-dependent oxidoreductase	-
BHE84_RS00460	101006..101743	-	738	WP_016849691.1	SDR family oxidoreductase	-
BHE84_RS00465	101869..102780	+	912	WP_016849690.1	LysR family transcriptional regulator	-
BHE84_RS00470	102977..104050	-	1074	WP_026006953.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T66214 WP_005928957.1 NZ_CP017188:99562-99861 [Xanthomonas citri pv. glycines str. 8ra]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHIMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T66214 NZ_CP017188:99562-99861 [Xanthomonas citri pv. glycines str. 8ra]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACATCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9674.20 Da
• Isoelectric Point: 9.8271

>AT66214 WP_016849693.1 NZ_CP017188:99317-99574 [Xanthomonas citri pv. glycines str. 8ra]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT66214 NZ_CP017188:99317-99574 [Xanthomonas citri pv. glycines str. 8ra]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A1D9ED60