Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/ElaA-DUF1778
Location 27885..28648 Replicon plasmid pDSMZ16690
Accession NZ_CP017185
Organism Enterobacter roggenkampii strain DSM 16690

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag BFV67_RS22435 Protein ID WP_069598995.1
Coordinates 28154..28648 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag BFV67_RS22430 Protein ID WP_069598994.1
Coordinates 27885..28163 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFV67_RS22425 25484..27745 - 2262 WP_069598993.1 type IV conjugative transfer system coupling protein TraD -
BFV67_RS22430 27885..28163 + 279 WP_069598994.1 DUF1778 domain-containing protein Antitoxin
BFV67_RS22435 28154..28648 + 495 WP_069598995.1 GNAT family N-acetyltransferase Toxin
BFV67_RS22440 28675..29412 - 738 WP_069598996.1 complement resistance protein TraT -
BFV67_RS22445 29557..30138 - 582 WP_069598997.1 protein traS -
BFV67_RS22450 30154..33039 - 2886 WP_069598998.1 conjugal transfer mating pair stabilization protein TraG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..151583 151583


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-86)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17987.76 Da        Isoelectric Point: 9.3683

>T66197 WP_069598995.1 NZ_CP017185:28154-28648 [Enterobacter roggenkampii]
MGISAPEPLKAGHNIADFCCSDQGLNEWLKKKAHKNHSTGISRVYVICAQNSQRVIGYYCLSTGSIQRKMAPGAYRRNSP
ESLPVIVLGRLAIDQSYCGKGLGAALLKDAIYRTENIALQAGVKALVVHALNEDVRSFYTRFGFDSSVVQPLTLLYPIKI
QTTE

Download         Length: 495 bp

>T66197 NZ_CP017185:28154-28648 [Enterobacter roggenkampii]
ATGGGAATAAGCGCACCAGAGCCACTCAAGGCCGGGCATAACATTGCTGATTTTTGTTGTTCCGATCAGGGGCTGAACGA
ATGGTTAAAAAAGAAAGCGCATAAAAACCACAGTACCGGCATTTCCCGCGTATATGTTATCTGCGCGCAGAACAGTCAAC
GGGTCATCGGTTATTATTGTTTATCGACAGGCAGTATTCAGAGAAAAATGGCTCCGGGTGCTTACAGGCGAAATTCACCA
GAATCCCTCCCCGTTATTGTTCTCGGCAGGCTTGCTATTGACCAGTCTTATTGCGGCAAGGGGCTTGGTGCTGCATTGCT
TAAGGATGCCATTTATCGCACTGAGAACATTGCACTACAGGCTGGTGTAAAAGCACTGGTTGTTCATGCCCTCAATGAGG
ACGTCAGAAGCTTCTACACCCGATTTGGCTTTGACTCTTCAGTCGTCCAGCCATTAACGCTGCTGTATCCGATTAAAATT
CAGACGACAGAGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10602.05 Da        Isoelectric Point: 4.4513

>AT66197 WP_069598994.1 NZ_CP017185:27885-28163 [Enterobacter roggenkampii]
MKTESRAAPINIRARESQRDLIDMAASLVSKSRTDFMLDVACREAQDILLDQRLFILDEEKYDAFVAELDAPITAERQAR
IDDLMSRKSPWE

Download         Length: 279 bp

>AT66197 NZ_CP017185:27885-28163 [Enterobacter roggenkampii]
ATGAAAACCGAATCCAGAGCGGCACCGATTAACATACGGGCAAGAGAATCACAGCGTGACCTCATCGACATGGCGGCAAG
CCTTGTCTCAAAATCGCGTACTGACTTTATGCTCGACGTTGCCTGCAGAGAGGCTCAGGACATACTTCTGGATCAGCGTC
TCTTTATCCTCGATGAGGAAAAATACGATGCTTTTGTTGCAGAGCTGGATGCTCCGATTACTGCCGAACGTCAGGCCAGA
ATCGATGACCTGATGAGCCGAAAATCGCCATGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References