Detailed information of TA system TA066140

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1591595..1592508
• Replicon: chromosome
• Accession: NZ_CP017180
• Organism: Enterobacter hormaechei subsp. oharae strain DSM 16687

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BFV66_RS07635
• Protein ID: WP_047052345.1
• Coordinates: 1591595..1592068 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BFV66_RS07640
• Protein ID: WP_047052347.1
• Coordinates: 1592065..1592508 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BFV66_RS07615	1587754..1589064	+	1311	WP_047052339.1	type I-F CRISPR-associated protein Csy1	-
BFV66_RS07620	1589061..1589996	+	936	WP_047052340.1	type I-F CRISPR-associated protein Csy2	-
BFV66_RS07625	1590010..1591008	+	999	WP_047052342.1	type I-F CRISPR-associated protein Csy3	-
BFV66_RS07630	1591018..1591572	+	555	WP_047052344.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
BFV66_RS07635	1591595..1592068	-	474	WP_047052345.1	RES domain-containing protein	Toxin
BFV66_RS07640	1592065..1592508	-	444	WP_047052347.1	DUF2384 domain-containing protein	Antitoxin
BFV66_RS07645	1594460..1594678	-	219	WP_002211347.1	translation initiation factor IF-1	-
BFV66_RS07650	1594963..1595667	-	705	WP_047052381.1	leucyl/phenylalanyl-tRNA--protein transferase	-
BFV66_RS07655	1595713..1597434	-	1722	WP_003858307.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (94-144)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17570.95 Da
• Isoelectric Point: 5.1151

>T66140 WP_047052345.1 NZ_CP017180:c1592068-1591595 [Enterobacter hormaechei subsp. oharae]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T66140 NZ_CP017180:c1592068-1591595 [Enterobacter hormaechei subsp. oharae]
ATGATTTTTTATCGTCTGGTAACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGAAGTGGTGCAAACCAGTATGGAGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCACGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTCAATTCTGTTGAATTACTGCCTTTTGATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16502.77 Da
• Isoelectric Point: 6.4819

>AT66140 WP_047052347.1 NZ_CP017180:c1592508-1592065 [Enterobacter hormaechei subsp. oharae]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT66140 NZ_CP017180:c1592508-1592065 [Enterobacter hormaechei subsp. oharae]
ATGAGAACATGGGTTCCTGCGCAAAGGTCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGTTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCACCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA