Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ataRT/DUF1778(antitoxin) |
| Location | 1682557..1683354 | Replicon | chromosome |
| Accession | NZ_CP017179 | ||
| Organism | Enterobacter hormaechei subsp. steigerwaltii strain DSM 16691 | ||
Toxin (Protein)
| Gene name | ataT | Uniprot ID | - |
| Locus tag | BFV68_RS07850 | Protein ID | WP_033487261.1 |
| Coordinates | 1682833..1683354 (+) | Length | 174 a.a. |
Antitoxin (Protein)
| Gene name | ataR | Uniprot ID | A0A331QJY7 |
| Locus tag | BFV68_RS07845 | Protein ID | WP_015570876.1 |
| Coordinates | 1682557..1682826 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BFV68_RS07810 | 1678096..1678455 | + | 360 | WP_017384779.1 | helix-turn-helix transcriptional regulator | - |
| BFV68_RS07815 | 1678465..1678629 | - | 165 | WP_017693668.1 | helix-turn-helix transcriptional regulator | - |
| BFV68_RS07820 | 1678784..1680025 | + | 1242 | WP_017693667.1 | bifunctional glucose-1-phosphatase/inositol phosphatase | - |
| BFV68_RS07825 | 1680058..1680285 | - | 228 | WP_006809324.1 | YccJ family protein | - |
| BFV68_RS07830 | 1680304..1680900 | - | 597 | WP_006809323.1 | NAD(P)H:quinone oxidoreductase | - |
| BFV68_RS07835 | 1681291..1681461 | + | 171 | WP_001273664.1 | general stress protein | - |
| BFV68_RS07840 | 1681578..1682483 | + | 906 | WP_017693666.1 | DMT family transporter | - |
| BFV68_RS07845 | 1682557..1682826 | + | 270 | WP_015570876.1 | DUF1778 domain-containing protein | Antitoxin |
| BFV68_RS07850 | 1682833..1683354 | + | 522 | WP_033487261.1 | GNAT family N-acetyltransferase | Toxin |
| BFV68_RS07855 | 1683413..1684735 | - | 1323 | WP_032670921.1 | pyrimidine utilization transport protein G | - |
| BFV68_RS07860 | 1684757..1685248 | - | 492 | WP_015570873.1 | pyrimidine utilization flavin reductase protein F | - |
| BFV68_RS07865 | 1685261..1685851 | - | 591 | WP_069595751.1 | malonic semialdehyde reductase | - |
| BFV68_RS07870 | 1685861..1686661 | - | 801 | WP_069595752.1 | pyrimidine utilization protein D | - |
| BFV68_RS07875 | 1686669..1687055 | - | 387 | WP_015570870.1 | pyrimidine utilization protein C | - |
| BFV68_RS07880 | 1687067..1687756 | - | 690 | WP_023296288.1 | pyrimidine utilization protein B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 174 a.a. Molecular weight: 19453.18 Da Isoelectric Point: 7.4318
>T66118 WP_033487261.1 NZ_CP017179:1682833-1683354 [Enterobacter hormaechei subsp. steigerwaltii]
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLVRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQS
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLVRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQS
Download Length: 522 bp
>T66118 NZ_CP017179:1682833-1683354 [Enterobacter hormaechei subsp. steigerwaltii]
GTGGCAAATCTCACGATCGAAATGTTATCAGAGGGAACCGATTACGATTTCGGCGATTTCGATTGTGGTGAACCCTCGCT
AAATGCCTTCCTTACCGAGCACCTGGTACGTCAGCACGGCGGGCGTATTTTACGCGGCTACCTGCTTAAAGAACGCGACC
ATCCGCGTGTCCTGGGCTATTACACACTCTCGGGAAGTTGCTTTGAAAAAGCGATGCTTCCTTCAAAGACTCAGCAGCGC
CGCATCCCATACAGCAACGTCCCCAGCGTGACGCTGGGGCGTCTGGCTGTCCATAAAGAACTCCAGGGAAACGAGTGGGG
AACAACGCTTGTCACACACGCTATGCGCGTTGTTTATCTGGCGTCGCAGGCTGTTGGCGTCCACGGAATTTTTGTGGATG
CGCTTAACGAACGGGCCAAACGATTTTATCTGAAGCTGGGGTTTATCCCGTTGGCAGGTGAAAACAGCAGTTCGCTGTTC
TTCCCCACGCAATCTATCGAACGACTGTTTGAGCAGTCGTGA
GTGGCAAATCTCACGATCGAAATGTTATCAGAGGGAACCGATTACGATTTCGGCGATTTCGATTGTGGTGAACCCTCGCT
AAATGCCTTCCTTACCGAGCACCTGGTACGTCAGCACGGCGGGCGTATTTTACGCGGCTACCTGCTTAAAGAACGCGACC
ATCCGCGTGTCCTGGGCTATTACACACTCTCGGGAAGTTGCTTTGAAAAAGCGATGCTTCCTTCAAAGACTCAGCAGCGC
CGCATCCCATACAGCAACGTCCCCAGCGTGACGCTGGGGCGTCTGGCTGTCCATAAAGAACTCCAGGGAAACGAGTGGGG
AACAACGCTTGTCACACACGCTATGCGCGTTGTTTATCTGGCGTCGCAGGCTGTTGGCGTCCACGGAATTTTTGTGGATG
CGCTTAACGAACGGGCCAAACGATTTTATCTGAAGCTGGGGTTTATCCCGTTGGCAGGTGAAAACAGCAGTTCGCTGTTC
TTCCCCACGCAATCTATCGAACGACTGTTTGAGCAGTCGTGA
Antitoxin
Download Length: 90 a.a. Molecular weight: 10247.75 Da Isoelectric Point: 5.8836
>AT66118 WP_015570876.1 NZ_CP017179:1682557-1682826 [Enterobacter hormaechei subsp. steigerwaltii]
MPALKKQRIDLRLSDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWIAVMDAIDNPPEPNERLKR
AAKRLRNME
MPALKKQRIDLRLSDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWIAVMDAIDNPPEPNERLKR
AAKRLRNME
Download Length: 270 bp
>AT66118 NZ_CP017179:1682557-1682826 [Enterobacter hormaechei subsp. steigerwaltii]
ATGCCAGCACTCAAAAAACAGCGTATCGATCTTCGCCTGTCGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACCAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCCGAAGTCATCGAACAGCATCGGCGTC
TCGTATTAAACGAAGCCTCATGGATTGCCGTTATGGATGCCATCGACAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
ATGCCAGCACTCAAAAAACAGCGTATCGATCTTCGCCTGTCGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACCAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCCGAAGTCATCGAACAGCATCGGCGTC
TCGTATTAAACGAAGCCTCATGGATTGCCGTTATGGATGCCATCGACAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|