Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3085528..3086330 Replicon chromosome
Accession NZ_CP017147
Organism Bosea vaviloviae strain Vaf18

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A1D7U256
Locus tag BHK69_RS14210 Protein ID WP_069690668.1
Coordinates 3085803..3086330 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A1D7U263
Locus tag BHK69_RS14205 Protein ID WP_069690667.1
Coordinates 3085528..3085806 (+) Length 93 a.a.

Genomic Context

BHK69_RS14185BHK69_RS14190BHK69_RS14195BHK69_RS14200BHK69_RS14205BHK69_RS14210BHK69_RS14180
Location: 3082446..3083006 (561 bp)
Type: Others
Protein ID: WP_069690664.1
Location: 3083027..3083614 (588 bp)
Type: Others
Protein ID: WP_069693657.1
Location: 3084059..3084871 (813 bp)
Type: Others
Protein ID: WP_069690665.1
Location: 3084868..3085314 (447 bp)
Type: Others
Protein ID: WP_069690666.1
Location: 3085528..3085806 (279 bp)
Type: Antitoxin
Protein ID: WP_069690667.1
Location: 3085803..3086330 (528 bp)
Type: Toxin
Protein ID: WP_069690668.1
Location: 3081374..3082345 (972 bp)
Type: Others
Protein ID: WP_069690663.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BHK69_RS141803081374..3082345-972WP_069690663.1LysR family transcriptional regulator-
BHK69_RS141853082446..3083006+561WP_069690664.1phosphonopyruvate decarboxylase-
BHK69_RS141903083027..3083614+588WP_069693657.1aldehyde dehydrogenase-
BHK69_RS141953084059..3084871+813WP_069690665.1SDR family oxidoreductase-
BHK69_RS142003084868..3085314+447WP_069690666.1VOC family protein-
BHK69_RS142053085528..3085806+279WP_069690667.1DUF1778 domain-containing proteinAntitoxin
BHK69_RS142103085803..3086330+528WP_069690668.1GNAT family N-acetyltransferaseToxin

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(5-89)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18949.77 Da        Isoelectric Point: 7.3745

>T66074 WP_069690668.1 NZ_CP017147:3085803-3086330 [Bosea vaviloviae]
VSLPAWHEEPITKAHDRKAFDCGVSELNRFLERFARQGHEHNAVKTFCAIADDTPNKVLGFYSLTPTSIAYEAVPPAMTR
GLARHRVAGFLLARLAVDKTVGGQGLGGQLLLAAALRCLRVTVEVGGVLLIIDAKDDRAAQWYCSFGAERAADQPLTLVA
PLTTFAEALRETGHL

Download         Length: 528 bp

>T66074 NZ_CP017147:3085803-3086330 [Bosea vaviloviae]
GTGAGCCTTCCCGCCTGGCATGAGGAGCCGATCACGAAGGCGCATGATCGAAAGGCCTTCGACTGCGGTGTGAGCGAGCT
GAATAGGTTCCTCGAGCGGTTTGCCCGGCAAGGGCATGAGCACAACGCCGTGAAGACGTTTTGCGCAATCGCGGACGACA
CACCCAACAAGGTCCTGGGGTTCTATAGCCTTACCCCAACCTCGATCGCATACGAGGCGGTTCCCCCTGCCATGACCAGG
GGGCTGGCCCGCCATAGGGTGGCTGGCTTCCTGCTCGCGCGGCTTGCCGTCGACAAGACCGTCGGCGGCCAAGGCCTCGG
CGGGCAGCTCCTCCTTGCGGCGGCTTTGCGTTGCCTGCGGGTGACGGTGGAAGTCGGCGGAGTTTTGCTGATCATCGACG
CCAAAGATGACCGCGCCGCGCAATGGTATTGCAGCTTTGGCGCGGAGCGAGCCGCCGACCAGCCGCTCACTCTGGTTGCG
CCACTGACCACCTTCGCTGAAGCGCTTCGCGAAACAGGGCACCTTTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10098.73 Da        Isoelectric Point: 11.0037

>AT66074 WP_069690667.1 NZ_CP017147:3085528-3085806 [Bosea vaviloviae]
MARTALDDTNRMNLRIKPDAKARLMRAAALRHTDLTSFVTQSALRAADAVIAEADVTKVSERDFFRILELLDNPPKPNAR
LKAAAAALPKSL

Download         Length: 279 bp

>AT66074 NZ_CP017147:3085528-3085806 [Bosea vaviloviae]
ATGGCACGCACCGCCCTTGACGACACAAATCGGATGAACCTCCGCATCAAGCCGGACGCGAAGGCGCGGCTGATGCGTGC
GGCTGCTCTGCGCCATACCGATCTGACCAGTTTCGTCACCCAGTCCGCCCTGCGCGCGGCCGATGCCGTCATCGCTGAAG
CCGATGTGACCAAGGTGTCGGAGCGTGACTTTTTTCGGATCCTGGAATTGCTGGACAACCCGCCAAAGCCGAATGCGAGG
TTGAAAGCCGCCGCCGCCGCCTTGCCGAAGTCCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1D7U256

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1D7U263

References