Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2939499..2940055 Replicon chromosome
Accession NZ_CP017147
Organism Bosea vaviloviae strain Vaf18

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BHK69_RS31395 Protein ID WP_083269369.1
Coordinates 2939499..2939789 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1D7U1V2
Locus tag BHK69_RS13520 Protein ID WP_069690560.1
Coordinates 2939777..2940055 (-) Length 93 a.a.

Genomic Context

BHK69_RS13500BHK69_RS13505BHK69_RS13510BHK69_RS13515BHK69_RS31395BHK69_RS13520BHK69_RS13525BHK69_RS13530BHK69_RS13535
Location: 2934984..2936057 (1074 bp)
Type: Others
Protein ID: WP_148663404.1
Location: 2936072..2937058 (987 bp)
Type: Others
Protein ID: WP_083269367.1
Location: 2937534..2938535 (1002 bp)
Type: Others
Protein ID: WP_083269368.1
Location: 2938646..2939101 (456 bp)
Type: Others
Protein ID: WP_069693629.1
Location: 2939499..2939789 (291 bp)
Type: Toxin
Protein ID: WP_083269369.1
Location: 2939777..2940055 (279 bp)
Type: Antitoxin
Protein ID: WP_069690560.1
Location: 2940276..2941481 (1206 bp)
Type: Others
Protein ID: WP_083269371.1
Location: 2941478..2943028 (1551 bp)
Type: Others
Protein ID: WP_069690561.1
Location: 2943224..2944291 (1068 bp)
Type: Others
Protein ID: WP_069690562.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BHK69_RS135002934984..2936057+1074WP_148663404.1alkene reductase-
BHK69_RS135052936072..2937058+987WP_083269367.1SDR family oxidoreductase-
BHK69_RS135102937534..2938535+1002WP_083269368.1tRNA dihydrouridine(20/20a) synthase DusA-
BHK69_RS135152938646..2939101+456WP_069693629.1PaaI family thioesterase-
BHK69_RS313952939499..2939789-291WP_083269369.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BHK69_RS135202939777..2940055-279WP_069690560.1CopG family ribbon-helix-helix proteinAntitoxin
BHK69_RS135252940276..2941481-1206WP_083269371.1sugar ABC transporter permease-
BHK69_RS135302941478..2943028-1551WP_069690561.1sugar ABC transporter ATP-binding protein-
BHK69_RS135352943224..2944291-1068WP_069690562.1sugar-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10723.24 Da        Isoelectric Point: 9.6540

>T66073 WP_083269369.1 NZ_CP017147:c2939789-2939499 [Bosea vaviloviae]
MPRVVFAPAAVRDLERLRAFLRSKDPSAAKRAGETIIAGTQALGTHPRMGRLVEDLPEQYREWLIDFGDSGYVVRYRVDS
DAVTILAVRHQKEAGS

Download         Length: 291 bp

>T66073 NZ_CP017147:c2939789-2939499 [Bosea vaviloviae]
ATGCCACGAGTAGTTTTCGCGCCTGCAGCGGTTCGCGATCTCGAGCGACTGCGCGCCTTCCTTCGCTCCAAGGACCCATC
AGCCGCCAAACGGGCGGGCGAGACGATCATCGCAGGCACGCAAGCACTCGGCACGCATCCTCGCATGGGCCGGCTTGTCG
AGGATCTACCCGAGCAATACCGGGAATGGCTCATCGATTTTGGGGATAGCGGATATGTGGTTCGCTATCGTGTTGACAGC
GACGCTGTAACAATCCTCGCGGTGCGGCACCAAAAGGAAGCGGGATCATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10606.87 Da        Isoelectric Point: 5.2082

>AT66073 WP_069690560.1 NZ_CP017147:c2940055-2939777 [Bosea vaviloviae]
MAAVTSIKLDDELKGRVQNLAAARRRTSHWIMREAIEQYVAREEKHEALRQDTVKAWEEFQATGLRATADEVEKWLSSWG
SENELPTPVCHE

Download         Length: 279 bp

>AT66073 NZ_CP017147:c2940055-2939777 [Bosea vaviloviae]
ATGGCAGCGGTCACATCCATCAAGCTTGACGATGAACTGAAGGGCCGTGTGCAGAACCTGGCCGCGGCGCGTCGGCGCAC
GTCTCATTGGATCATGCGCGAGGCAATTGAGCAGTACGTGGCGCGTGAAGAGAAGCACGAAGCGTTGCGACAAGACACAG
TTAAGGCCTGGGAGGAATTTCAAGCCACCGGCTTGCGCGCAACGGCTGATGAGGTCGAAAAGTGGTTGTCGAGTTGGGGG
TCTGAAAACGAACTGCCCACGCCGGTATGCCACGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1D7U1V2

References