Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-DUF971
Location 2554510..2555107 Replicon chromosome
Accession NZ_CP017147
Organism Bosea vaviloviae strain Vaf18

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BHK69_RS31365 Protein ID WP_083269273.1
Coordinates 2554802..2555107 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BHK69_RS11905 Protein ID WP_148663384.1
Coordinates 2554510..2554818 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHK69_RS11890 2549869..2551518 + 1650 WP_083269272.1 ABC transporter substrate-binding protein -
BHK69_RS11895 2551523..2552935 + 1413 WP_069690285.1 amidase -
BHK69_RS11900 2553226..2554449 + 1224 WP_069690286.1 MFS transporter -
BHK69_RS11905 2554510..2554818 - 309 WP_148663384.1 putative addiction module antidote protein Antitoxin
BHK69_RS31365 2554802..2555107 - 306 WP_083269273.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BHK69_RS11915 2555175..2556077 - 903 WP_069690288.1 DMT family transporter -
BHK69_RS11920 2556124..2557044 - 921 WP_069690289.1 pirin family protein -
BHK69_RS11925 2557128..2557688 - 561 WP_069690290.1 NAD(P)H-dependent oxidoreductase -
BHK69_RS11930 2557774..2558694 + 921 WP_069690291.1 LysR family transcriptional regulator -
BHK69_RS11935 2558846..2559892 + 1047 WP_069690292.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-91)

Antitoxin

Uncharacterized protein HI1420

(11-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11453.16 Da        Isoelectric Point: 10.6457

>T66072 WP_083269273.1 NZ_CP017147:c2555107-2554802 [Bosea vaviloviae]
MQIEVLPAFDRWLAGIRDAEARRRIATRLLRLQRGNPGDGRFLRDGVSELKIDHGPGYRVYYAKRGDILLLLLGGGDKAT
QARDIEKAIGDLKGWQHERKS

Download         Length: 306 bp

>T66072 NZ_CP017147:c2555107-2554802 [Bosea vaviloviae]
ATGCAGATTGAGGTTCTGCCGGCATTCGATCGGTGGCTTGCTGGTATACGTGATGCCGAAGCCCGGCGTCGGATCGCGAC
GCGCCTGCTTCGGCTGCAGCGAGGCAACCCCGGCGACGGACGCTTCCTGCGCGACGGCGTCAGCGAACTGAAGATCGATC
ATGGGCCGGGATATCGCGTCTACTACGCGAAACGCGGCGACATCCTCCTCCTGCTCCTCGGTGGCGGCGACAAAGCTACG
CAAGCCAGGGATATCGAGAAAGCGATTGGCGACCTGAAAGGATGGCAGCATGAGCGGAAATCCTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10490.05 Da        Isoelectric Point: 5.0022

>AT66072 WP_148663384.1 NZ_CP017147:c2554818-2554510 [Bosea vaviloviae]
MSGNPDHISRPFDIAELVGDPIVAQGFIADAVATGDAAEIAEAIGIVARAQGMSKLASDAGMSRESLYRALSPKGNPTLS
TLLVVLKALGFKLSGVERINPA

Download         Length: 309 bp

>AT66072 NZ_CP017147:c2554818-2554510 [Bosea vaviloviae]
ATGAGCGGAAATCCTGACCATATCTCCAGGCCATTCGACATTGCCGAACTCGTCGGCGATCCAATCGTCGCGCAGGGCTT
CATTGCAGACGCCGTTGCCACAGGGGACGCGGCCGAGATCGCAGAAGCGATCGGCATTGTCGCGCGAGCACAAGGCATGT
CGAAGCTGGCCAGCGACGCCGGGATGTCGCGCGAATCGCTGTATCGGGCCCTCAGCCCCAAGGGAAATCCGACACTCAGC
ACCTTGCTCGTCGTCCTGAAAGCGCTCGGCTTCAAGCTCAGCGGCGTCGAACGTATCAATCCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References