Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-shpB/BrnT_toxin-BrnA
Location 1852996..1853521 Replicon chromosome
Accession NZ_CP017147
Organism Bosea vaviloviae strain Vaf18

Toxin (Protein)


Gene name brnT Uniprot ID A0A1D7TZJ8
Locus tag BHK69_RS08670 Protein ID WP_069689744.1
Coordinates 1853246..1853521 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID A0A1D7TZH8
Locus tag BHK69_RS08665 Protein ID WP_069689743.1
Coordinates 1852996..1853262 (-) Length 89 a.a.

Genomic Context

BHK69_RS08650BHK69_RS08655BHK69_RS08675BHK69_RS08680BHK69_RS08690BHK69_RS08640BHK69_RS08645BHK69_RS08660BHK69_RS08665BHK69_RS08670BHK69_RS08685
Location: 1849621..1850406 (786 bp)
Type: Others
Protein ID: WP_069689741.1
Location: 1850452..1852257 (1806 bp)
Type: Others
Protein ID: WP_069693491.1
Location: 1853654..1854532 (879 bp)
Type: Others
Protein ID: WP_069693492.1
Location: 1854590..1856317 (1728 bp)
Type: Others
Protein ID: WP_083269206.1
Location: 1857491..1858183 (693 bp)
Type: Others
Protein ID: WP_069689746.1
Location: 1848264..1848794 (531 bp)
Type: Others
Protein ID: WP_069693490.1
Location: 1848818..1849384 (567 bp)
Type: Others
Protein ID: WP_199579216.1
Location: 1852286..1852996 (711 bp)
Type: Others
Protein ID: WP_083269822.1
Location: 1852996..1853262 (267 bp)
Type: Antitoxin
Protein ID: WP_069689743.1
Location: 1853246..1853521 (276 bp)
Type: Toxin
Protein ID: WP_069689744.1
Location: 1856450..1857247 (798 bp)
Type: Others
Protein ID: WP_069689745.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BHK69_RS086401848264..1848794-531WP_069693490.1GNAT family N-acetyltransferase-
BHK69_RS086451848818..1849384-567WP_199579216.1helix-turn-helix domain-containing protein-
BHK69_RS086501849621..1850406+786WP_069689741.1hypothetical protein-
BHK69_RS086551850452..1852257+1806WP_069693491.1translation elongation factor 4-
BHK69_RS086601852286..1852996-711WP_083269822.1HAD family phosphatase-
BHK69_RS086651852996..1853262-267WP_069689743.1BrnA antitoxin family proteinAntitoxin
BHK69_RS086701853246..1853521-276WP_069689744.1BrnT family toxinToxin
BHK69_RS086751853654..1854532+879WP_069693492.1sulfoxide reductase heme-binding subunit YedZ-
BHK69_RS086801854590..1856317+1728WP_083269206.1MFS transporter-
BHK69_RS086851856450..1857247-798WP_069689745.1undecaprenyl-diphosphate phosphatase-
BHK69_RS086901857491..1858183+693WP_069689746.1glutathione S-transferase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-83)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(26-80)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10435.80 Da        Isoelectric Point: 5.1875

>T66070 WP_069689744.1 NZ_CP017147:c1853521-1853246 [Bosea vaviloviae]
IPEFEWDPEKDTANVAKHGVAFEFAKRIFEGPVLSWVDDRVDYGEVREISIGRVDGIVVLVVVHTDRDGRIRIISARPVS
QKERQRYEASL

Download         Length: 276 bp

>T66070 NZ_CP017147:c1853521-1853246 [Bosea vaviloviae]
ATACCTGAATTCGAATGGGATCCTGAGAAGGACACGGCCAATGTCGCCAAGCACGGCGTCGCCTTCGAATTTGCGAAACG
CATTTTCGAGGGACCGGTGCTGAGCTGGGTCGATGACCGCGTCGACTATGGCGAGGTTCGAGAGATCAGCATCGGTCGTG
TCGACGGCATCGTTGTGCTCGTCGTCGTGCATACCGACCGCGACGGCCGCATCCGCATCATCTCGGCCCGACCGGTCTCT
CAAAAGGAAAGGCAGCGCTATGAAGCCTCCCTATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10115.55 Da        Isoelectric Point: 8.3958

>AT66070 WP_069689743.1 NZ_CP017147:c1853262-1852996 [Bosea vaviloviae]
MKPPYDKPLSPEALAALKDDEIDFSDIPELDETFWKNAKLVEPDRTQLVTLRVKKSVLEAYKAQGRGYQTRMNAVLETYA
RSQLKRTS

Download         Length: 267 bp

>AT66070 NZ_CP017147:c1853262-1852996 [Bosea vaviloviae]
ATGAAGCCTCCCTATGACAAACCGCTGTCGCCTGAGGCTCTCGCCGCGCTCAAGGACGACGAAATCGATTTCAGCGACAT
CCCCGAGCTGGACGAGACCTTCTGGAAAAACGCGAAGCTGGTCGAGCCCGACCGGACGCAACTGGTGACTCTGCGCGTCA
AGAAATCGGTCCTGGAAGCCTATAAGGCCCAGGGCCGCGGCTATCAGACCCGCATGAACGCCGTTCTCGAAACCTATGCC
CGTTCCCAACTCAAGCGGACTTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1D7TZJ8

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1D7TZH8

References