Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1278143..1278680 Replicon chromosome
Accession NZ_CP017147
Organism Bosea vaviloviae strain Vaf18

Toxin (Protein)


Gene name parE Uniprot ID A0A1D7TY91
Locus tag BHK69_RS06065 Protein ID WP_069689319.1
Coordinates 1278390..1278680 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1D7TYB1
Locus tag BHK69_RS06060 Protein ID WP_069689318.1
Coordinates 1278143..1278400 (+) Length 86 a.a.

Genomic Context

BHK69_RS31305BHK69_RS06045BHK69_RS06050BHK69_RS06055BHK69_RS06060BHK69_RS06065BHK69_RS06075BHK69_RS06040BHK69_RS06070
Location: 1273335..1274174 (840 bp)
Type: Others
Protein ID: WP_083269152.1
Location: 1275339..1276730 (1392 bp)
Type: Others
Protein ID: WP_148663644.1
Location: 1276829..1277182 (354 bp)
Type: Others
Protein ID: WP_069689316.1
Location: 1277229..1278086 (858 bp)
Type: Others
Protein ID: WP_069689317.1
Location: 1278143..1278400 (258 bp)
Type: Antitoxin
Protein ID: WP_069689318.1
Location: 1278390..1278680 (291 bp)
Type: Toxin
Protein ID: WP_069689319.1
Location: 1281641..1283476 (1836 bp)
Type: Others
Protein ID: WP_069689321.1
Location: 1274346..1275191 (846 bp)
Type: Others
Protein ID: WP_083269805.1
Location: 1278699..1281443 (2745 bp)
Type: Others
Protein ID: WP_069689320.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BHK69_RS313051273335..1274174+840WP_083269152.1endonuclease/exonuclease/phosphatase family protein-
BHK69_RS060401274346..1275191-846WP_083269805.1tetratricopeptide repeat protein-
BHK69_RS060451275339..1276730+1392WP_148663644.1leucyl aminopeptidase family protein-
BHK69_RS060501276829..1277182+354WP_069689316.1MarR family transcriptional regulator-
BHK69_RS060551277229..1278086+858WP_069689317.1C40 family peptidase-
BHK69_RS060601278143..1278400+258WP_069689318.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
BHK69_RS060651278390..1278680+291WP_069689319.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BHK69_RS060701278699..1281443-2745WP_069689320.1DNA mismatch repair protein MutS-
BHK69_RS060751281641..1283476+1836WP_069689321.1PAS domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Antitoxin ParD

(6-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11058.59 Da        Isoelectric Point: 6.0741

>T66069 WP_069689319.1 NZ_CP017147:1278390-1278680 [Bosea vaviloviae]
MAVRRTPRADQDLVGIYLEGVGQFGQRQAEIYAANLSSCFELLASQPLMARERTEIQPPVRVHAHGSHIIVYAVDEEDIL
IMRVLHGRRDWEREFQ

Download         Length: 291 bp

>T66069 NZ_CP017147:1278390-1278680 [Bosea vaviloviae]
ATGGCGGTTAGGCGAACGCCGCGAGCCGACCAGGATCTGGTCGGGATTTATCTCGAAGGCGTCGGGCAATTCGGGCAAAG
GCAAGCCGAGATTTACGCGGCCAACCTTAGTTCATGCTTCGAATTGCTCGCCTCCCAGCCTTTGATGGCGCGAGAGCGAA
CGGAAATTCAACCGCCGGTCCGGGTGCATGCCCATGGCAGTCATATCATCGTCTACGCAGTCGATGAGGAGGACATCCTG
ATCATGCGCGTCCTGCACGGCCGTCGCGATTGGGAACGCGAGTTTCAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9642.70 Da        Isoelectric Point: 4.8660

>AT66069 WP_069689318.1 NZ_CP017147:1278143-1278400 [Bosea vaviloviae]
MATMNVSLPDQMKAWVETQAESGRYGNASDYVRDLIRRDQERQDKIAAFQRLIDEGRASGVSTRALDEVWEEARRRAKEL
GLDGG

Download         Length: 258 bp

>AT66069 NZ_CP017147:1278143-1278400 [Bosea vaviloviae]
ATGGCGACGATGAACGTGTCCCTACCCGACCAGATGAAGGCCTGGGTCGAGACGCAGGCCGAGAGCGGCCGCTACGGCAA
CGCCAGCGACTATGTCCGCGACCTGATCCGGCGCGACCAGGAGCGGCAGGACAAGATCGCAGCATTCCAGCGGCTGATCG
ATGAAGGCCGCGCTAGCGGCGTCAGCACGCGGGCTTTGGACGAGGTCTGGGAGGAGGCCCGTCGCCGCGCCAAAGAGCTT
GGCCTCGATGGCGGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1D7TY91

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1D7TYB1

References