66013

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 542978..543509 Replicon chromosome
Accession NZ_CP017111
Organism Sulfurospirillum halorespirans DSM 13726 strain PCE-M2

Toxin (Protein)


Gene name relE Uniprot ID A0A1D7TH29
Locus tag SHALO_RS02715 Protein ID WP_069477267.1
Coordinates 543219..543509 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1D7THK9
Locus tag SHALO_RS02710 Protein ID WP_069477266.1
Coordinates 542978..543229 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHALO_RS02695 538500..539093 + 594 WP_069477263.1 ORF6N domain-containing protein -
SHALO_RS02700 539231..540166 + 936 WP_069477264.1 SIR2 family protein -
SHALO_RS02705 540163..542889 + 2727 WP_069477265.1 hypothetical protein -
SHALO_RS02710 542978..543229 + 252 WP_069477266.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SHALO_RS02715 543219..543509 + 291 WP_069477267.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SHALO_RS02720 543621..546458 + 2838 WP_069477268.1 transporter substrate-binding domain-containing protein -
SHALO_RS02725 546476..547654 - 1179 WP_069477269.1 sugar transporter -
SHALO_RS02730 547792..548193 + 402 WP_069477270.1 SEC-C domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11341.28 Da        Isoelectric Point: 10.2211

>T66013 WP_069477267.1 NZ_CP017111:543219-543509 [Sulfurospirillum halorespirans DSM 13726]
MSYELEFHPQALKEWKNLGETIKEQFKKKLKERLENQKVPQDKLIGVDAVYKIKLKSFGYRLAYEVIDERVVVMVLAVGK
RENNKVYNALHSRFGK

Download         Length: 291 bp

>T66013 NZ_CP017111:543219-543509 [Sulfurospirillum halorespirans DSM 13726]
ATGAGTTATGAGTTAGAATTTCACCCACAAGCGCTTAAAGAGTGGAAGAATTTGGGTGAGACCATTAAAGAGCAGTTTAA
AAAGAAGCTAAAAGAGCGACTAGAAAACCAAAAAGTTCCCCAAGACAAGCTGATTGGAGTTGATGCTGTCTATAAAATAA
AACTCAAATCATTTGGCTATCGACTTGCGTATGAAGTGATTGATGAGAGAGTTGTTGTTATGGTATTGGCGGTTGGAAAA
AGAGAAAACAACAAAGTGTACAATGCCCTTCATTCACGATTTGGCAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9307.71 Da        Isoelectric Point: 4.4797

>AT66013 WP_069477266.1 NZ_CP017111:542978-543229 [Sulfurospirillum halorespirans DSM 13726]
MQPILSNYTASITELKKSPTQILENAGDEVIAILNHNVVSAYLVPSKTYEKLMAMLDDYMLSKEVTSRQSEAYTPIKVTL
DEL

Download         Length: 252 bp

>AT66013 NZ_CP017111:542978-543229 [Sulfurospirillum halorespirans DSM 13726]
ATGCAACCTATTTTATCCAACTACACCGCCAGTATTACTGAGCTTAAAAAATCACCGACGCAAATTCTTGAAAATGCGGG
TGATGAAGTTATTGCTATACTCAATCACAATGTGGTGAGTGCCTATCTGGTGCCTTCTAAAACGTATGAAAAATTGATGG
CGATGTTGGATGATTATATGCTCTCCAAAGAAGTCACAAGCAGGCAAAGCGAAGCTTATACGCCCATCAAAGTAACGCTT
GATGAGTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7TH29

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7THK9

References