Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 41218..42733 Replicon plasmid pRgalIE4872c
Accession NZ_CP017104
Organism Rhizobium gallicum strain IE4872

Toxin (Protein)


Gene name rlegT Uniprot ID A0A1L5NQC0
Locus tag IE4872_RS22815 Protein ID WP_074070669.1
Coordinates 41218..42021 (-) Length 268 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A1L5NQ99
Locus tag IE4872_RS22820 Protein ID WP_074070670.1
Coordinates 42131..42733 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IE4872_RS22815 41218..42021 - 804 WP_074070669.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IE4872_RS22820 42131..42733 - 603 WP_074070670.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IE4872_RS22825 42834..46904 + 4071 WP_074070671.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..506339 506339


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(2-231)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-50)


Sequences

Toxin        


Download         Length: 268 a.a.        Molecular weight: 29656.01 Da        Isoelectric Point: 4.6900

>T66007 WP_074070669.1 NZ_CP017104:c42021-41218 [Rhizobium gallicum]
MLFRLSQSGARNRYVLKGAMLFVTWPEHVFRPTGDLDLLGHGDPDPDAIIETFQQICAVQADDGLHFDLASIKVEPVREA
DKYQGARVMLEGELAKAIIRVQVDIGFGDHVYPAPKLANFPSILPDLPEATILMYPPETVVAEKFEAMIRFGLANGRIKD
FYDIWLTTQIFQFQLTTVIDAVAGTLARRETAIPTTMPEGLSEGYAAIAEERGLWRGFLERNPPAIGPPSFPELQLQLGR
FFGPVVAGLNNSGAGDSRWDPDMKVWR

Download         Length: 804 bp

>T66007 NZ_CP017104:c42021-41218 [Rhizobium gallicum]
TTGCTGTTTCGCCTCAGCCAGTCGGGCGCGCGGAACCGCTACGTCCTCAAGGGCGCGATGCTCTTTGTGACCTGGCCCGA
ACATGTCTTTCGACCGACCGGCGATCTCGATCTCCTAGGTCACGGTGATCCAGACCCGGATGCGATAATTGAAACCTTTC
AGCAAATCTGTGCGGTCCAAGCCGACGACGGTTTGCACTTCGACCTCGCGAGCATCAAGGTCGAACCGGTTCGGGAGGCC
GACAAGTATCAGGGCGCTCGTGTCATGCTGGAGGGCGAGCTCGCCAAAGCGATCATTCGAGTGCAAGTTGACATCGGCTT
CGGAGATCATGTCTATCCGGCGCCTAAGCTCGCGAACTTCCCGAGCATTCTTCCGGATCTGCCCGAGGCGACGATCCTGA
TGTATCCGCCCGAGACCGTCGTCGCAGAGAAGTTTGAAGCAATGATCCGCTTCGGACTGGCAAATGGTCGGATCAAGGAT
TTCTATGACATCTGGCTCACGACGCAGATTTTTCAATTTCAGCTCACGACCGTCATCGACGCCGTCGCCGGCACGCTGGC
GCGACGGGAAACCGCTATCCCGACGACGATGCCGGAAGGTCTTTCGGAAGGCTATGCTGCTATCGCAGAGGAAAGGGGCC
TGTGGCGTGGCTTCCTGGAACGCAATCCACCCGCGATCGGCCCGCCCTCTTTTCCGGAGCTTCAACTTCAGCTCGGGCGT
TTTTTCGGTCCAGTTGTCGCAGGGCTCAACAATTCCGGCGCTGGCGACAGTAGATGGGATCCGGACATGAAAGTTTGGCG
GTAG

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22160.69 Da        Isoelectric Point: 9.4096

>AT66007 WP_074070670.1 NZ_CP017104:c42733-42131 [Rhizobium gallicum]
MNYRDSALELARSRGIVRARDFKSAGIPLVYLKRLTDSGDLVRLGRGLYQDPDRVGEHVAHDLAEAARLMANGTVCLISA
LRQHELTTQLPHAVWMMIPHKARAPISPSFPVKIVRASGDALTSGIERISVEGVDVPIYGVAKTVADCFKYRRLVGEDVA
VEALRDALRDRKTTPGELMKYAVIDRCSARMEPLIRALQE

Download         Length: 603 bp

>AT66007 NZ_CP017104:c42733-42131 [Rhizobium gallicum]
ATGAATTATCGGGATAGCGCGCTCGAACTGGCCAGATCTCGCGGCATCGTGCGGGCCCGAGATTTCAAGTCGGCGGGCAT
TCCACTCGTATATCTGAAACGCCTGACCGATTCCGGCGACCTCGTGCGACTCGGACGTGGACTGTATCAGGACCCGGACC
GCGTCGGTGAGCACGTCGCGCACGATCTGGCTGAAGCTGCCCGGCTGATGGCGAACGGCACTGTCTGCCTGATCAGCGCA
CTTCGCCAACACGAACTGACCACTCAGCTGCCGCATGCGGTCTGGATGATGATCCCCCATAAAGCACGAGCGCCGATATC
ACCATCGTTTCCGGTAAAAATCGTTCGGGCAAGCGGTGACGCGCTCACATCCGGAATTGAAAGGATCTCGGTAGAAGGTG
TCGACGTGCCTATCTACGGCGTGGCGAAAACGGTAGCGGACTGCTTCAAATATCGGCGCCTCGTTGGCGAGGACGTCGCG
GTCGAAGCGCTTCGCGATGCCCTGCGCGATCGCAAGACGACACCAGGTGAGCTGATGAAATACGCGGTGATCGACCGATG
CTCCGCACGCATGGAGCCTCTTATCCGGGCGCTACAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L5NQC0

Antitoxin

Source ID Structure
AlphaFold DB A0A1L5NQ99

References