Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1870149..1870420 Replicon chromosome
Accession NZ_CP017100
Organism Escherichia coli strain K-12 NEB 5-alpha

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1870187..1870290 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1870149..1870420 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NEB5A_RS09430 1867306..1868745 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NEB5A_RS09435 1868863..1869099 + 237 WP_001295499.1 DUF1480 family protein -
NEB5A_RS09440 1869204..1869395 + 192 WP_000457842.1 YebW family protein -
NEB5A_RS09445 1869396..1870052 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1870149..1870420 + 272 - - Antitoxin
- 1870187..1870290 - 104 - - Toxin
NEB5A_RS09455 1870448..1870789 - 342 WP_000976476.1 YebY family protein -
NEB5A_RS09460 1870802..1871674 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NEB5A_RS09465 1871678..1872052 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NEB5A_RS09470 1872191..1872421 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NEB5A_RS09475 1872523..1873179 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
NEB5A_RS09480 1873203..1873865 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T65979 NZ_CP017100:c1870290-1870187 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT65979 NZ_CP017100:1870149-1870420 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References