Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1881055..1881827 Replicon chromosome
Accession NZ_CP017087
Organism Enterobacter sp. HK169

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag EnteroDNA1_RS08890 Protein ID WP_165587293.1
Coordinates 1881459..1881827 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag EnteroDNA1_RS08885 Protein ID WP_047058006.1
Coordinates 1881055..1881414 (+) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EnteroDNA1_RS08845 1876277..1877134 + 858 WP_047058026.1 hypothetical protein -
EnteroDNA1_RS08850 1877412..1877876 + 465 WP_004114621.1 hypothetical protein -
EnteroDNA1_RS08855 1877931..1878290 + 360 WP_004136901.1 hypothetical protein -
EnteroDNA1_RS08860 1878375..1878587 + 213 WP_047058010.1 hypothetical protein -
EnteroDNA1_RS08865 1878694..1879515 + 822 WP_069303200.1 DUF945 domain-containing protein -
EnteroDNA1_RS08870 1879595..1880074 + 480 WP_075206252.1 antirestriction protein -
EnteroDNA1_RS21785 1880085..1880318 + 234 Protein_1753 hypothetical protein -
EnteroDNA1_RS08875 1880315..1880797 + 483 WP_047058008.1 DNA repair protein RadC -
EnteroDNA1_RS08880 1880811..1881032 + 222 WP_032938028.1 DUF987 domain-containing protein -
EnteroDNA1_RS08885 1881055..1881414 + 360 WP_047058006.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EnteroDNA1_RS08890 1881459..1881827 + 369 WP_165587293.1 TA system toxin CbtA family protein Toxin
EnteroDNA1_RS08895 1881907..1882227 - 321 WP_047058025.1 hypothetical protein -
EnteroDNA1_RS08900 1882366..1883355 - 990 WP_069303201.1 glycosyltransferase -
EnteroDNA1_RS08905 1884128..1885036 - 909 WP_047058003.1 kdo(2)-lipid IV(A) palmitoleoyltransferase -
EnteroDNA1_RS22470 1885238..1885510 - 273 WP_177952593.1 hypothetical protein -
EnteroDNA1_RS08915 1885920..1886153 + 234 WP_004132711.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1852922..1886153 33231


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(7-110)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13676.65 Da        Isoelectric Point: 9.7700

>T65902 WP_165587293.1 NZ_CP017087:1881459-1881827 [Enterobacter sp. HK169]
IQSLPPQRAASSRLSSVKIWQKLLEYLLEQHYGLTLNDTPFGNDSMIQKHIDAGISLCDAVNFIVEKYDLVRTDRHGFSV
KEQSPFIGSLDMLRDRKATGLMTRKGYKTVTDITGGRFSGGK

Download         Length: 369 bp

>T65902 NZ_CP017087:1881459-1881827 [Enterobacter sp. HK169]
ATACAATCCCTGCCCCCTCAAAGGGCGGCATCGTCACGTCTGTCATCAGTCAAAATCTGGCAAAAATTACTGGAGTATCT
GCTGGAGCAACACTACGGCCTTACCCTCAACGACACACCGTTTGGCAACGACAGTATGATCCAGAAACACATTGATGCGG
GAATCTCACTGTGTGACGCTGTGAATTTTATCGTGGAAAAGTACGACCTGGTGCGTACTGACCGTCACGGCTTCAGCGTG
AAAGAGCAGTCTCCGTTTATCGGCAGCCTTGATATGCTCCGAGACCGGAAGGCTACCGGGCTGATGACCCGCAAGGGATA
TAAAACCGTTACTGACATCACAGGTGGCAGATTCAGCGGAGGGAAATAA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13409.59 Da        Isoelectric Point: 8.8636

>AT65902 WP_047058006.1 NZ_CP017087:1881055-1881414 [Enterobacter sp. HK169]
MQKATRVINHNIAEPWWGLRRNVTPCFGARLVQEGNRLHYLADRASTTGTFNDSDLRHLDQAFPLLMKQMELMLTSSELM
PRIQRCITLHAKGLICKADTLGSCGYLYIVIYPASATTA

Download         Length: 360 bp

>AT65902 NZ_CP017087:1881055-1881414 [Enterobacter sp. HK169]
ATGCAGAAAGCAACCCGTGTAATCAACCATAACATCGCGGAACCCTGGTGGGGCCTCAGACGCAACGTCACGCCATGTTT
TGGTGCCCGGCTGGTACAGGAGGGTAACCGCCTGCATTACCTTGCTGACCGCGCCAGCACCACCGGGACATTTAATGACT
CAGATTTACGCCATCTGGACCAGGCATTTCCGTTACTGATGAAGCAGATGGAGCTCATGCTGACCAGCAGCGAACTCATG
CCCCGCATTCAGCGCTGCATCACGCTCCATGCAAAAGGGCTGATATGTAAGGCCGATACGCTCGGTTCCTGTGGCTATTT
GTATATCGTAATTTATCCGGCGTCTGCAACAACCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References