Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2113347..2113984 Replicon chromosome
Accession NZ_CP017024
Organism Pseudomonas psychrotolerans strain KNF2016

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BGI51_RS09760 Protein ID WP_133862346.1
Coordinates 2113347..2113760 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag BGI51_RS09765 Protein ID WP_133862345.1
Coordinates 2113760..2113984 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BGI51_RS09735 2108892..2110247 + 1356 WP_187980978.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase -
BGI51_RS09740 2110247..2110879 + 633 WP_007161189.1 flavin prenyltransferase UbiX -
BGI51_RS09745 2110872..2111168 + 297 WP_187980979.1 YceK/YidQ family lipoprotein -
BGI51_RS09750 2111165..2112568 - 1404 WP_187980980.1 PLP-dependent aminotransferase family protein -
BGI51_RS09755 2112830..2113306 - 477 WP_133862347.1 YbaK/EbsC family protein -
BGI51_RS09760 2113347..2113760 - 414 WP_133862346.1 type II toxin-antitoxin system VapC family toxin Toxin
BGI51_RS09765 2113760..2113984 - 225 WP_133862345.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BGI51_RS09770 2114050..2115426 - 1377 WP_187980981.1 L-serine ammonia-lyase -
BGI51_RS09775 2115553..2116488 + 936 WP_187980982.1 LysR family transcriptional regulator -
BGI51_RS09780 2116974..2117615 - 642 WP_007161182.1 oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

SpoVT-AbrB domain

(7-42)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15528.64 Da        Isoelectric Point: 6.9499

>T65817 WP_133862346.1 NZ_CP017024:c2113760-2113347 [Pseudomonas psychrotolerans]
VPARYLLDTNICIYIAKHNPPQVRERFARHGRDELAMSAITWGELCHGAAKSQQPERTRTILEQLRQQIAVLELDTECAE
HYGAIRAELERQGKIIGNNDLWIAAHARARALILVSNNLREFSRVADLACENWTAAD

Download         Length: 414 bp

>T65817 NZ_CP017024:c2113760-2113347 [Pseudomonas psychrotolerans]
GTGCCTGCTCGCTACCTGCTCGACACCAACATCTGCATCTACATCGCCAAGCACAATCCGCCGCAGGTCCGTGAGCGCTT
CGCCCGGCATGGTCGCGATGAACTGGCGATGTCTGCGATCACCTGGGGTGAGCTCTGTCATGGCGCGGCCAAGAGTCAGC
AACCCGAGCGCACCCGGACGATCCTGGAACAGCTCCGCCAGCAGATCGCCGTGCTGGAGCTGGATACGGAATGCGCCGAA
CACTATGGCGCCATCCGCGCCGAGCTGGAGCGCCAGGGCAAGATCATCGGCAACAACGATCTGTGGATCGCCGCCCATGC
CCGCGCCAGGGCGCTGATCCTGGTCAGCAACAATCTGCGGGAGTTCAGCCGGGTCGCCGATCTGGCCTGCGAAAACTGGA
CAGCAGCCGATTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8524.57 Da        Isoelectric Point: 4.5230

>AT65817 WP_133862345.1 NZ_CP017024:c2113984-2113760 [Pseudomonas psychrotolerans]
MAEARVFKSGNSQALRLPKEFRFESDRVEIFRRGDEIVLRELRPDAADIFDTLAALSLATLEREDSPPQAREEF

Download         Length: 225 bp

>AT65817 NZ_CP017024:c2113984-2113760 [Pseudomonas psychrotolerans]
ATGGCCGAAGCCCGCGTGTTCAAGTCCGGTAACAGCCAGGCCTTGCGCCTGCCCAAGGAATTTCGCTTCGAATCGGATCG
GGTGGAAATCTTCCGCCGCGGCGACGAGATCGTTCTGCGGGAATTGCGGCCAGATGCCGCCGATATCTTCGACACCCTGG
CCGCGCTGTCATTGGCGACCCTGGAACGGGAAGACAGCCCACCCCAGGCGCGGGAAGAGTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References