Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4946447..4947114 Replicon chromosome
Accession NZ_CP017020
Organism Xanthomonas citri pv. malvacearum strain MSCT

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag BGK55_RS21270 Protein ID WP_005916679.1
Coordinates 4946698..4947114 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag BGK55_RS21265 Protein ID WP_005916676.1
Coordinates 4946447..4946701 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BGK55_RS23770 4942553..4942762 + 210 WP_108350128.1 RNA 2'-phosphotransferase -
BGK55_RS21245 4942945..4944210 + 1266 WP_005916664.1 cardiolipin synthase B -
BGK55_RS21250 4944236..4944763 - 528 WP_005916668.1 hypothetical protein -
BGK55_RS21255 4945002..4945208 + 207 WP_003489327.1 hypothetical protein -
BGK55_RS21260 4945195..4946301 + 1107 WP_005916674.1 type II toxin-antitoxin system RelE/ParE family toxin -
BGK55_RS21265 4946447..4946701 + 255 WP_005916676.1 Arc family DNA-binding protein Antitoxin
BGK55_RS21270 4946698..4947114 + 417 WP_005916679.1 type II toxin-antitoxin system VapC family toxin Toxin
BGK55_RS21275 4947442..4948404 - 963 WP_005916682.1 IS1595 family transposase -
BGK55_RS24975 4948423..4948884 - 462 WP_125825520.1 hypothetical protein -
BGK55_RS21290 4950063..4950389 + 327 WP_005912355.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T65814 WP_005916679.1 NZ_CP017020:4946698-4947114 [Xanthomonas citri pv. malvacearum]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T65814 NZ_CP017020:4946698-4947114 [Xanthomonas citri pv. malvacearum]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAGGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACGGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTGGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT65814 WP_005916676.1 NZ_CP017020:4946447-4946701 [Xanthomonas citri pv. malvacearum]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT65814 NZ_CP017020:4946447-4946701 [Xanthomonas citri pv. malvacearum]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4U0C6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YKJ0

References