65813

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4545851..4546212 Replicon chromosome
Accession NZ_CP017020
Organism Xanthomonas citri pv. malvacearum strain MSCT

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BGK55_RS19660 Protein ID WP_005914328.1
Coordinates 4545851..4545985 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag BGK55_RS19665 Protein ID WP_003486606.1
Coordinates 4546060..4546212 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BGK55_RS19640 4540988..4542679 - 1692 WP_033481741.1 M20/M25/M40 family metallo-hydrolase -
BGK55_RS19645 4542871..4543905 - 1035 WP_050554793.1 MBL fold metallo-hydrolase -
BGK55_RS19650 4543944..4545233 - 1290 WP_005914329.1 tryptophan--tRNA ligase -
BGK55_RS19655 4545415..4545624 - 210 WP_003486601.1 CsbD family protein -
BGK55_RS19660 4545851..4545985 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BGK55_RS19665 4546060..4546212 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
BGK55_RS19670 4546319..4547242 - 924 WP_005914327.1 arginase -
BGK55_RS19675 4547563..4548015 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
BGK55_RS19680 4548079..4548438 + 360 WP_005914325.1 hypothetical protein -
BGK55_RS19685 4548535..4549452 + 918 WP_033481739.1 hypothetical protein -
BGK55_RS19690 4549449..4549991 + 543 WP_003486615.1 GTPase -
BGK55_RS19695 4550473..4551156 + 684 WP_003486617.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T65813 WP_005914328.1 NZ_CP017020:c4545985-4545851 [Xanthomonas citri pv. malvacearum]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T65813 NZ_CP017020:c4545985-4545851 [Xanthomonas citri pv. malvacearum]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTATCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT65813 WP_003486606.1 NZ_CP017020:c4546212-4546060 [Xanthomonas citri pv. malvacearum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT65813 NZ_CP017020:c4546212-4546060 [Xanthomonas citri pv. malvacearum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References